(Q42486150)

English

Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation

scientific article published on June 2000

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 November 2017

Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

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author name string

Venable CL

1

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Frevert EU

2

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Europe PubMed Central

PubMed publication ID

1 November 2017

Kim YB

3

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Fischer BM

4

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Kamatkar S

5

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Neel BG

6

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Kahn BB

7

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

language of work or name

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publication date

1 June 2000

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Europe PubMed Central

PubMed publication ID

1 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

1 November 2017

275

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Europe PubMed Central

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1 November 2017

24

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Europe PubMed Central

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1 November 2017

18318-18326

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Europe PubMed Central

PubMed publication ID

1 November 2017

Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

The insulin signalling system and the IRS proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

From receptor to transporter: insulin signalling to glucose transport.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Increased abundance of specific skeletal muscle protein-tyrosine phosphatases in a genetic model of insulin-resistant obesity and diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Abnormal Regulation of Protein Tyrosine Phosphatase Activities in Skeletal Muscle of Insulin-Resistant Humans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Regulation of the insulin signalling pathway by cellular protein-tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Cloning of a cDNA for a major human protein-tyrosine-phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Adenovirus-mediated overexpression of IRS-1 interacting domains abolishes insulin-stimulated mitogenesis without affecting glucose transport in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Protein tyrosine phosphatase 1B interacts with the activated insulin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Evidence for an insulin receptor substrate 1 independent insulin signaling pathway that mediates insulin-responsive glucose transporter (GLUT4) translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Two naturally occurring mutant insulin receptors phosphorylate insulin receptor substrate-1 (IRS-1) but fail to mediate the biological effects of insulin. Evidence that IRS-1 phosphorylation is not sufficient for normal insulin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Targeting of constitutively active phosphoinositide 3-kinase to GLUT4-containing vesicles in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Defect in skeletal muscle phosphatidylinositol-3-kinase in obese insulin-resistant mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908392199

21 January 2018

Identifiers

10.1074/JBC.M908392199

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

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