(Q42493391)

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G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model

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Europe PubMed Central

PubMed publication ID

1 November 2017

G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

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Mara Dierssen Sotos

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M Dierssen

4

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author name string

C Baamonde

1

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

C Martínez-Cué

2

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Europe PubMed Central

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1 November 2017

J Flórez

3

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Europe PubMed Central

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1 November 2017

publication date

25 August 2011

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Europe PubMed Central

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1 November 2017

Developmental Neuroscience

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Europe PubMed Central

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1 November 2017

33

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Europe PubMed Central

PubMed publication ID

1 November 2017

5

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Europe PubMed Central

PubMed publication ID

1 November 2017

442-450

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Europe PubMed Central

PubMed publication ID

1 November 2017

Aneuploidy: from a physiological mechanism of variance to Down syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Cognitive deficits and associated neurological complications in individuals with Down's syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Behavioral, cognitive and biochemical responses to different environmental conditions in male Ts65Dn mice, a model of Down syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Pitfalls and hopes in Down syndrome therapeutic approaches: in the search for evidence-based treatments.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

A mouse model for Down syndrome exhibits learning and behaviour deficits.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Operant conditioning in the Ts65Dn mouse: learning.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

A behavioral assessment of Ts65Dn mice: a putative Down syndrome model.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Impaired short- and long-term memory in Ts65Dn mice, a model for Down syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

A murine model for Down syndrome shows reduced responsiveness to pain.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Experimental parameters affecting the Morris water maze performance of a mouse model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Behavioral validation of the Ts65Dn mouse model for Down syndrome of a genetic background free of the retinal degeneration mutation Pde6b(rd1).

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

beta-Adrenergic modulation of muscarinic cholinergic receptor expression and function in developing heart

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Lipid abnormalities in the brain in adult Down's syndrome and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Phospholipid composition and levels are altered in Down syndrome brain

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Polyol profiles in Down syndrome. myo-Inositol, specifically, is elevated in the cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Reduced phospholipase C-beta activity and isoform expression in the cerebellum of TS65Dn mouse: a model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Impaired cyclic AMP production in the hippocampus of a Down syndrome murine model

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Developmental pattern of muscarinic receptors in normal and Down's syndrome fetal brain — An autoradiographic study

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Fetal Down syndrome brains exhibit aberrant levels of neurotransmitters critical for normal brain development

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

A gel-based proteomic method reveals several protein pathway abnormalities in fetal Down syndrome brain.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Decreased neurogenesis after cholinergic forebrain lesion in the adult rat.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Fetal human brain exhibits a prenatal peak in the density of serotonin 5-HT1A receptors

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with Down syndrome.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Postnatal handling induces long-term modifications in central beta-noradrenergic signalling in rats

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Short-term effects of postnatal manipulation on central beta-adrenoceptor transmission.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

The effects of piracetam on cognitive performance in a mouse model of Down's syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Hippocampal volume and neuronal number in Ts65Dn mice: a murine model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Hippocampal hypocellularity in the Ts65Dn mouse originates early in development

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: a model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Speeding of miniature excitatory post-synaptic currents in Ts65Dn cultured hippocampal neurons

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

The neuropsychology of Down syndrome: evidence for hippocampal dysfunction

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Transmembrane signaling through phospholipase C in human cortical membranes.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Neural induction is mediated by cross-talk between the protein kinase C and cyclic AMP pathways.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Hippocampal myo-inositol and cognitive ability in adults with Down syndrome: an in vivo proton magnetic resonance spectroscopy study

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Similar deficits of central histaminergic system in patients with Down syndrome and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Early Environmental Stimulation Produces Long-Lasting Changes on β-Adrenoceptor Transduction System

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Neuronal activity and adenylyl cyclase in environment-dependent plasticity of axonal outgrowth in Drosophila

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Inhibition of cAMP response element-binding protein reduces neuronal excitability and plasticity, and triggers neurodegeneration

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

The cyclic AMP cascade is altered in the fragile X nervous system

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Autism: review of neurochemical investigation.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Phospholipase C-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Modification of glutamate receptors by phospholipase A2: its role in adaptive neural plasticity

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Environmental enrichment mitigates the effects of basal forebrain lesions on cognitive flexibility.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

The influences of rearing environment and neonatal choline dietary supplementation on spatial learning and memory in adult rats.

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Neurotrophic signaling molecules associated with cholinergic damage in young and aged rats: environmental enrichment as potential therapeutic agent

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

The combination of human neuronal serotonergic cell implants and environmental enrichment after contusive SCI improves motor recovery over each individual strategy

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Effect of long-lasting serotonin depletion on environmental enrichment-induced neurogenesis in adult rat hippocampus and spatial learning

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Developmental forebrain cholinergic lesion and environmental enrichment: behaviour, CA1 cytoarchitecture and neurogenesis

1 reference

https://api.crossref.org/works/10.1159%2F000329425

21 January 2018

Identifiers

10.1159/000329425

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

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