(Q42498384)

1 November 2017

A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity (English)

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1 November 2017

Goldoni S

1

1 reference

1 November 2017

Iozzo RA

2

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1 November 2017

Kay P

3

1 reference

1 November 2017

Campbell S

4

1 reference

1 November 2017

McQuillan A

5

1 reference

1 November 2017

Agnew C

6

1 reference

1 November 2017

Zhu JX

7

1 reference

1 November 2017

Keene DR

8

1 reference

1 November 2017

Reed CC

9

1 reference

1 November 2017

Iozzo RV

10

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1 November 2017

language of work or name

English

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publication date

17 July 2006

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1 November 2017

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1 November 2017

26

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1 November 2017

368-381

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1 November 2017

3

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209803

1 November 2017

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cites work

Bipartite inhibition of Drosophila epidermal growth factor receptor by the extracellular and transmembrane domains of Kekkon1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Knockouts of Kekkon1 define sequence elements essential for Drosophila epidermal growth factor receptor inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Epidermal growth factor receptor distribution during chemotactic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Receptors for epidermal growth factor and other polypeptide mitogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Localization and modulation of ErbB receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Conservation of an inhibitor of the epidermal growth factor receptor, Kekkon1, in dipterans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Anti-epidermal growth factor receptor antibodies inhibit the autocrine-stimulated growth of MDA-468 human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Epidermal growth factor receptor gene-amplified MDA-468 breast cancer cell line and its nonamplified variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Biologically active decorin is a monomer in solution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Characterization and tissue-specific expression of human LRIG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Matrix proteoglycans: from molecular design to cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Decorin is a biological ligand for the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Grb2 regulates internalization of EGF receptors through clathrin-coated pits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Decorin binds near the C terminus of type I collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Properties of the extracellular calcium binding module of the proteoglycan testican

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Tyrosine kinase inhibition: an approach to drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Multiple positive and negative regulators of signaling by the EGF-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Fibroblast growth factor-binding protein is a novel partner for perlecan protein core

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

The Drosophila kekkon genes: novel members of both the leucine-rich repeat and immunoglobulin superfamilies expressed in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Cloning, characterization, and expression of human LIG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Decorin prevents metastatic spreading of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Negative regulation of receptor tyrosine kinases: unexpected links to c-Cbl and receptor ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Signal transduction. Autoinhibition control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Clathrin-independent endocytosis of ubiquitinated cargos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

cDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

LRIG1 and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT--PCR and immunohistochemical analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Production of an Epidermal Growth Factor Receptor-Related Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

The EGF receptor: a nexus for trafficking and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

7 January 2021

Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

7 January 2021

LRIG1 protein in human cells and tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

7 January 2021

Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209803

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209803

1 reference

Dimensions Publication ID

1 November 2017

0 references

1 reference