(Q42499319)

1 November 2017

title

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation (English)

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1 November 2017

Paul J Thornalley

11

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author name string

Mingzhan Xue

1

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1 November 2017

Naila Rabbani

2

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1 November 2017

Hiroshi Momiji

3

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1 November 2017

Precious Imbasi

4

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1 November 2017

M Maqsud Anwar

5

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1 November 2017

Neil Kitteringham

6

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1 November 2017

B Kevin Park

7

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1 November 2017

Tomokazu Souma

8

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1 November 2017

Takashi Moriguchi

9

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1 November 2017

Masayuki Yamamoto

10

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1 November 2017

language of work or name

English

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publication date

1 April 2012

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1 November 2017

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1 November 2017

volume

443

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1 November 2017

issue

1

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1 November 2017

page(s)

213-222

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The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal.

1 November 2017

cites work

1 reference

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Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

21 January 2018

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Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance

21 January 2018

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Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification

21 January 2018

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Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy

21 January 2018

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Dicarbonyl-induced accelerated aging in vitro in human skin fibroblasts

21 January 2018

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21 January 2018

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Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity

21 January 2018

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DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets.

21 January 2018

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Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins

21 January 2018

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Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

21 January 2018

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Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

21 January 2018

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The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

21 January 2018

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Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1

21 January 2018

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A simplified method for the purification of human red blood cell glyoxalase. I. Characteristics, immunoblotting, and inhibitor studies

21 January 2018

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Degradation products of proteins damaged by glycation, oxidation and nitration in clinical type 1 diabetes.

21 January 2018

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

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Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages

21 January 2018

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Genomic sequence of human glyoxalase-I: analysis of promoter activity and its regulation

21 January 2018

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Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes

21 January 2018

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GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2.

21 January 2018

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Differential expression and stability of endogenous nuclear factor E2-related factor 2 (Nrf2) by natural chemopreventive compounds in HepG2 human hepatoma cells.

21 January 2018

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The "comparative growth assay": examining the interplay of anti-cancer agents with cells carrying single gene alterations

21 January 2018

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Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetes

21 January 2018

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Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation

21 January 2018

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Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice

21 January 2018

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A proteomic view on the role of glucose in peritoneal dialysis

21 January 2018

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Role for glyoxalase I in Alzheimer's disease.

21 January 2018

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Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress

21 January 2018

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The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy

21 January 2018

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The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO)

21 January 2018

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Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

21 January 2018

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Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

21 January 2018

1 reference

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Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats

21 January 2018

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Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro.

21 January 2018

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Ordered organelle degradation during starvation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

The dicarbonyl proteome: proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes

21 January 2018

1 reference

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Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro

21 January 2018

1 reference

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Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Glycation of LDL by methylglyoxal increases arterial atherogenicity: a possible contributor to increased risk of cardiovascular disease in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Glyoxalase in diabetes, obesity and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

Identification of polymorphic antioxidant response elements in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111648

21 January 2018

Identifiers

DOI

10.1042/BJ20111648

1 reference

1 November 2017

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