(Q42506028)

English

Microsomal prostaglandin E synthase-1 deficiency is associated with elevated peroxisome proliferator-activated receptor gamma: regulation by prostaglandin E2 via the phosphatidylinositol 3-kinase and Akt pathway

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 November 2017

Microsomal prostaglandin E synthase-1 deficiency is associated with elevated peroxisome proliferator-activated receptor gamma: regulation by prostaglandin E2 via the phosphatidylinositol 3-kinase and Akt pathway (English)

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Europe PubMed Central

PubMed publication ID

1 November 2017

prostaglandin E2

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based on heuristic

inferred from title

Leslie J. Crofford

5

object named as

Leslie J Crofford

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Europe PubMed Central

PubMed publication ID

1 November 2017

author name string

Mohit Kapoor

1

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Europe PubMed Central

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1 November 2017

Fumiaki Kojima

2

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Europe PubMed Central

PubMed publication ID

1 November 2017

Min Qian

3

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Europe PubMed Central

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1 November 2017

Lihua Yang

4

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Europe PubMed Central

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1 November 2017

language of work or name

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publication date

22 December 2006

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Europe PubMed Central

PubMed publication ID

1 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

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1 November 2017

282

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Europe PubMed Central

PubMed publication ID

1 November 2017

8

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Europe PubMed Central

PubMed publication ID

1 November 2017

5356-5366

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Europe PubMed Central

PubMed publication ID

1 November 2017

Prostaglandin biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

EP2 and EP4 prostanoid receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E2 is an enhancer of interleukin-1beta-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Inhibitory effect of PPAR-gamma activator on IL-6 and mPGES protein expression in PBMC induced by homocysteine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Resolution of inflammation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces chronic colonic inflammation in rats.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E2 augments IL-10 signaling and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E2 increases growth and motility of colorectal carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E2 induces interleukin-8 gene transcription by activating C/EBP homologous protein in human T lymphocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E synthase in the pathophysiology of arthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Atorvastatin reduces the expression of prostaglandin E2 receptors in human carotid atherosclerotic plaques and monocytic cells: potential implications for plaque stabilization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Expression of prostaglandin E synthase mRNA is induced in beta-amyloid treated rat astrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Prostaglandin E2 production in ovarian cancer cell lines is regulated by cyclooxygenase-1, not cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

PPAR gamma ligands inhibit nitrotyrosine formation and inflammatory mediator expressions in adjuvant-induced rheumatoid arthritis mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610153200

21 January 2018

Identifiers

10.1074/JBC.M610153200

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

ResearchGate publication ID

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