(Q42515656)

1 November 2017

Distinct structural changes in a G protein-coupled receptor caused by different classes of agonist ligands (English)

1 reference

G protein-coupled receptor

1 November 2017

0 references

author

Kenneth A. Jacobson

5

1 reference

1 November 2017

Jian Hua Li

1

1 reference

1 November 2017

Sung-Jun Han

2

1 reference

1 November 2017

Fadi F Hamdan

3

1 reference

1 November 2017

Soo-Kyung Kim

4

1 reference

1 November 2017

Lanh M Bloodworth

6

1 reference

1 November 2017

Xiaohong Zhang

7

1 reference

1 November 2017

Jürgen Wess

8

1 reference

1 November 2017

language of work or name

English

0 references

publication date

10 July 2007

1 reference

Journal of Biological Chemistry

1 November 2017

1 reference

1 November 2017

282

1 reference

1 November 2017

36

1 reference

1 November 2017

26284-26293

1 reference

Molecular tinkering of G protein-coupled receptors: an evolutionary success

1 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

International Union of Pharmacology. XLVI. G protein-coupled receptor list.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Receptor activation: what does the rhodopsin structure tell us?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Rhodopsin: insights from recent structural studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Inverse, protean, and ligand-selective agonism: matters of receptor conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Mechanisms of inverse agonism at G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Constitutive activity and inverse agonists of G protein-coupled receptors: a current perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Differential transcriptional activation in vitro by NF-kappa B/Rel proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Molecular basis of inverse agonism in a G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Coupling ligand structure to specific conformational switches in the beta2-adrenoceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Muscarinic receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Molecular biology of muscarinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Conformational changes that occur during M3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Pronounced conformational changes following agonist activation of the M(3) muscarinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Use of an in situ disulfide cross-linking strategy to study the dynamic properties of the cytoplasmic end of transmembrane domain VI of the M3 muscarinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Role of the PAR1 receptor 8th helix in signaling: the 7-8-1 receptor activation mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Characterization of the residues in helix 8 of the human beta1-adrenergic receptor that are involved in coupling the receptor to G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Constitutive activity and inverse agonism at the M2 muscarinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Identification and molecular characterization of m3 muscarinic receptor dimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Quantitative analysis of muscarinic acetylcholine receptor homo- and heterodimerization in live cells: regulation of receptor down-regulation by heterodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Functional reconstitution in situ of 5-hydroxytryptamine2c (5HT2c) receptors with alphaq and inverse agonism of 5HT2c receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Light-induced exposure of the cytoplasmic end of transmembrane helix seven in rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704875200

21 January 2018

Identifiers

DOI

10.1074/JBC.M704875200

1 reference

1 November 2017

1 reference