(Q42516303)

English

Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells

scientific article published on 19 November 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

1 reference

based on heuristic

inferred from title

Theresa L. Powell

3

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

author name string

Fredrick J Rosario

1

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Yoshikatsu Kanai

2

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Thomas Jansson

4

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

language of work or name

0 references

publication date

19 November 2012

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Journal of Physiology

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

591

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

609-625

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

A unifying model for mTORC1-mediated regulation of mRNA translation.

1 reference

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27 August 2018

Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters

1 reference

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27 August 2018

Facilitated transporters mediate net efflux of amino acids to the fetus across the basal membrane of the placental syncytiotrophoblast.

1 reference

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27 August 2018

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

1 reference

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27 August 2018

Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

Isolation of plasma membrane vesicles from mouse placenta at term and measurement of system A and system beta amino acid transporter activity

1 reference

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27 August 2018

Adaptations in placental phenotype support fetal growth during undernutrition of pregnant mice.

1 reference

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27 August 2018

Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1

1 reference

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27 August 2018

Comparison of the transport characteristics of bioactive substances in IUGR and normal placentas

1 reference

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27 August 2018

New insights into mTOR signaling: mTORC2 and beyond

1 reference

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27 August 2018

Molecular mechanisms of mTOR-mediated translational control

1 reference

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27 August 2018

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

1 reference

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27 August 2018

Methods for siRNA-mediated reduction of mRNA and protein expression in human placental explants, isolated primary cells and cell lines.

1 reference

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27 August 2018

Regulation of placental amino acid transporter activity by mammalian target of rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

1 reference

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27 August 2018

Effect of in utero and early-life conditions on adult health and disease

1 reference

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27 August 2018

Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction.

1 reference

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27 August 2018

Maternal hormones linking maternal body mass index and dietary intake to birth weight

1 reference

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27 August 2018

Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity

1 reference

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27 August 2018

Expanding mTOR signaling

1 reference

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27 August 2018

Controlling cell growth and survival through regulated nutrient transporter expression

1 reference

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27 August 2018

Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

Amino acid transporter ATA2 is stored at the trans-Golgi network and released by insulin stimulus in adipocytes

1 reference

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27 August 2018

Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

IFPA 2005 Award in Placentology Lecture. Human placental transport in altered fetal growth: does the placenta function as a nutrient sensor? -- a review

1 reference

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27 August 2018

Placental phenotypes of intrauterine growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

Minireview: recent developments in the regulation of glucose transporter-4 traffic: new signals, locations, and partners

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

SNAT4 isoform of system A amino acid transporter is expressed in human placenta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2

1 reference

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27 August 2018

Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells

1 reference

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Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule

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Living with the past: evolution, development, and patterns of disease

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27 August 2018

An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival

1 reference

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Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: role in cell growth

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27 August 2018

CATs and HATs: the SLC7 family of amino acid transporters

1 reference

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27 August 2018

Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells

1 reference

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27 August 2018

Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family

1 reference

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27 August 2018

Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments.

1 reference

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27 August 2018

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

1 reference

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The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation

1 reference

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27 August 2018

Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes

1 reference

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27 August 2018

Insulin promotes the cell surface recruitment of the SAT2/ATA2 system A amino acid transporter from an endosomal compartment in skeletal muscle cells

1 reference

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27 August 2018

Function and structure of heterodimeric amino acid transporters

1 reference

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27 August 2018

Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A.

1 reference

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Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport

1 reference

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27 August 2018

L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-re

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27 August 2018

Development and polarization of cationic amino acid transporters and regulators in the human placenta

1 reference

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27 August 2018

Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids

1 reference

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27 August 2018

Placental transport of leucine and lysine is reduced in intrauterine growth restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

Intrauterine growth restriction is associated with a reduced activity of placental taurine transporters

1 reference

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27 August 2018

TOR signalling and control of cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

27 August 2018

Altered activity of the system A amino acid transporter in microvillous membrane vesicles from placentas of macrosomic babies born to diabetic women

1 reference

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27 August 2018

Placental transfer of glucose and amino acids in intrauterine growth retardation: studies with substrate analogs in the awake guinea pig.

1 reference

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27 August 2018

A fibrin matrix modulates the proliferation, hormone secretion and morphologic differentiation of cultured human placental trophoblast

1 reference

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27 August 2018

Purification, Characterization, andin vitroDifferentiation of Cytotrophoblasts from Human Term Placentae*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3577540

1 December 2018

Differential expression of the receptors for epidermal growth factor and insulin in the developing human placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of IL-6 and TNF-α on fatty acid uptake in cultured human primary trophoblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of hypoxia on human trophoblast in culture: morphology, glucose transport and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro cultured human term cytotrophoblast: a model for normal primary epithelial cells demonstrating a spontaneous differentiation programme that requires EGF for extensive development of syncytium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between the activity of the system A amino acid transporter in the microvillous plasma membrane of the human placenta and severity of fetal compromise in intrauterine growth restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired cytotrophoblast cell-cell fusion is associated with reduced Syncytin and increased apoptosis in patients with placental dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbohydrate metabolism in pregnancy. XVII. Diurnal profiles of plasma glucose, insulin, free fatty acids, triglycerides, cholesterol, and individual amino acids in late normal pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23165769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1113/JPHYSIOL.2012.238014

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

ResearchGate publication ID

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