(Q42516714)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

2

1 reference

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2 January 2020

author name string

Salvatore C Ruffolo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Xiling Yuan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Sylvie Desmarais

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Jean Himms-Hagen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Wanda Cromlish

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Kenny K Wong

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Brian P Kennedy

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

language of work or name

English

0 references

publication date

30 July 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17664276%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

issue

42

1 reference

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2 January 2020

page(s)

30423-30433

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Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells

2 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

TOR signaling in growth and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Heterozygous knockout of the IRS-1 gene in mice enhances obesity-linked insulin resistance: a possible model for the development of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Structure, regulation and function of PKB/AKT--a major therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Ribosomal S6 kinase signaling and the control of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Differential regulation of S6 phosphorylation by insulin and epidermal growth factor in Swiss mouse 3T3 cells: insulin activation of type 1 phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Metabolism of lipids in human white adipocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Current therapeutic options in type 2 diabetes mellitus: a practical approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

PTP1B regulates leptin signal transduction in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Neuronal PTP1B regulates body weight, adiposity and leptin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Role of amino acids in insulin signaling in adipocytes and their potential to decrease insulin resistance of adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Signaling pathways: the benefits of good communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200

Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700697200