(Q42518736)

1 November 2017

Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation (English)

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1 November 2017

Maya Dajee

1

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1 November 2017

Masahito Tarutani

2

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1 November 2017

Helen Deng

3

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1 November 2017

Ti Cai

4

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1 November 2017

Paul A Khavari

5

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1 November 2017

language of work or name

English

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publication date

1 February 2002

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1 November 2017

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1 November 2017

21

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1 November 2017

1527-1538

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1 November 2017

10

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205287

1 November 2017

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cites work

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Corrective gene transfer in the human skin disorder lamellar ichthyosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Ras proteins in the control of the cell cycle and cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Characterization of two monoclonal antibodies to human epidermal keratohyalin: reactivity with filaggrin and related proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

High-efficiency gene transfer and pharmacologic selection of genetically engineered human keratinocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Relationship between Ras pathways and cell cycle control.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Multiple ras effector pathways contribute to G(1) cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Creation of human tumour cells with defined genetic elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

New monoclonal antibodies recognizing epidermal differentiation-associated keratins in formalin-fixed, paraffin-embedded tissue. Keratin 10 expression in carcinoma of the vulva

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

The ras signaling pathway mimics insulin action on glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Small GTPases and cell cycle regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Ras gene mutation and amplification in human nonmelanoma skin cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Ras-independent Activation of the Raf/MEK/ERK Pathway upon Calcium-induced Differentiation of Keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Analysis of the transcriptional program induced by Raf in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Understanding Ras: 'it ain't over 'til it's over'.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

The dominant negative Ras mutant, N17Ras, can inhibit signaling independently of blocking Ras activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Expression of human cystatin A by keratinocytes is positively regulated via the Ras/MEKK1/MKK7/JNK signal transduction pathway but negatively regulated via the Ras/Raf-1/MEK1/ERK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

The murine N-ras gene is not essential for growth and development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Epidermal stem cells: markers, patterning and the control of stem cell fate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Multiple Ras functions can contribute to mammalian cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Signaling via beta1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205287

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205287

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Dimensions Publication ID

1 November 2017

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1 reference