(Q42525644)

1 November 2017

Inflammatory signal transduction in Crohn's disease and novel therapeutic approaches (English)

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1 November 2017

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Maikel P Peppelenbosch

object named as

Maikel Peppelenbosch

2

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author name string

Catherine van Montfrans

1

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1 November 2017

Anje A te Velde

3

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1 November 2017

Sander van Deventer

4

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1 November 2017

language of work or name

English

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publication date

1 September 2002

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1 November 2017

Biochemical Pharmacology

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1 November 2017

64

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1 November 2017

5-6

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1 November 2017

789-795

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Incidence of Crohn's disease in Stockholm County 1955-1989.

1 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Inflammatory bowel disease: etiology and pathogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Interleukin-10-deficient mice develop chronic enterocolitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Bacteria-specific T-cell clones are selective in their reactivity towards different enterobacteria or H. pylori and increased in inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Mechanisms of phagocytosis in macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

A synthetic mimetic of CD4 is able to suppress disease in a rodent model of immune colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

CD4 antibody treatment in patients with active Crohn's disease: a phase 1 dose finding study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Intraepithelial lymphocytes: exploring the Third Way in immunology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin‐2‐deficient colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Review article: the limitations of corticosteroid therapy in Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Medical therapy for induction and maintenance of remission in pouchitis: a systematic review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Methotrexate for the Treatment of Crohn's Disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Infliximab for the treatment of fistulas in patients with Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: A European multicenter trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Infliximab is the drug we have been waiting for in Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

The role of small intestinal antigen-presenting cells in the induction of T-cell reactivity to soluble protein antigens: association between aberrant presentation in the lamina propria and oral tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Oral tolerance, an active immunologic process mediated by multiple mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Immunobiology of dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Dendritic cells as a tool to induce anergic and regulatory T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

A family of human receptors structurally related to Drosophila Toll

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3beta receptor CCR7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Lymphocyte homing and homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Functional diversity of helper T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Cloning of a new cytokine that induces IFN-gamma production by T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

T(H)1 and T(H)2 cells: a historical perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Reciprocal control of T helper cell and dendritic cell differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

The roles of CD28 and CD40 ligand in T cell activation and tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Distinct roles of L-selectin and integrins alpha 4 beta 7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: the multistep model confirmed and refined

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Lamina propria T cells in Crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Immunoregulatory function of human intestinal mucosa lymphoid cells: evidence for enhanced suppressor cell activity in inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

In situ expression of interleukin-10 in noninflamed human gut and in inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

IL-10 secretion and sensitivity in normal human intestine and inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Low ileal interleukin 10 concentrations are predictive of endoscopic recurrence in patients with Crohn's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Transforming growth factor-betas and their signaling receptors are coexpressed in Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

Smoking and Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901140-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(02)01140-1

1 reference

1 November 2017

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