(Q42545581)

English

Effect of dietary fat on codon 12 and 13 Ha-ras gene mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced rat mammary gland tumors

scientific article published on December 1997

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scholarly article

1 reference

Europe PubMed Central

2 November 2017

Effect of dietary fat on codon 12 and 13 Ha-ras gene mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced rat mammary gland tumors (English)

1 reference

Europe PubMed Central

2 November 2017

author name string

Roberts-Thomson SJ

1

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Europe PubMed Central

2 November 2017

Snyderwine EG

2

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Europe PubMed Central

2 November 2017

publication date

1 December 1997

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Europe PubMed Central

2 November 2017

Molecular Carcinogenesis

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Europe PubMed Central

2 November 2017

20

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Europe PubMed Central

2 November 2017

4

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Europe PubMed Central

2 November 2017

348-354

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Europe PubMed Central

2 November 2017

Exposure to heterocyclic amines

1 reference

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Identification of the mutagens in cooked beef

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Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research

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21 January 2018

Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) carcinogenicity in rats.

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Possible mechanisms for PhIP-DNA adduct formation in the mammary gland of female Sprague-Dawley rats

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21 January 2018

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

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21 January 2018

Mutational activation of c-Ha-ras gene in squamous cell carcinomas of rat Zymbal gland induced by carcinogenic heterocyclic amines

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21 January 2018

Infrequent mutation of Ha-ras and p53 in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

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Dietary carcinogens and mammary carcinogenesis. Induction of rat mammary carcinomas by administration of heterocyclic amines in cooked foods

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Mutation and repair induced by the carcinogen 2-(hydroxyamino)-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in the dihydrofolate reductase gene of Chinese hamster ovary cells and conformational modeling of the dG-C8-PhIP adduct in DNA.

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N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations

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Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations.

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Detection of guanine-C8-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine adduct as a single spot on thin-layer chromatography by modification of the 32P-postlabeling method.

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21 January 2018

Role of polyunsaturated fatty acids as signal transducers: amplification of signals from growth factor receptors by fatty acids in mammary epithelial cells

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Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C.

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Rasmay mediate mammary cancer promotion by high fat

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The effect of GTPase activating protein upon ras is inhibited by mitogenically responsive lipids

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A cytoplasmic protein inhibits the GTPase activity of H-Ras in a phospholipid-dependent manner

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Role of GTP-binding proteins in the polyunsaturated fatty acid stimulated proliferation of mouse mammary epithelial cells

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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Selective pressures and ras activation in carcinogenesis

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21 January 2018

A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

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Induction of mammary tumors in female Sprague-Dawley rats by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and effect of dietary fat

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21 January 2018

High frequency and low specificity of ras gene mutations in rat Zymbal's gland tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline

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Identification of N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA

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21 January 2018

Identifiers

10.1002/(SICI)1098-2744(199712)20:4<348::AID-MC4>3.0.CO;2-F

1 reference

Europe PubMed Central

2 November 2017

1 reference

Europe PubMed Central

2 November 2017

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