(Q42558334)

6 July 2018

title

Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists (English)

1 reference

6 July 2018

author name string

K A Jacobson

1

1 reference

6 July 2018

C Gallo-Rodriguez

2

1 reference

6 July 2018

N Melman

3

1 reference

6 July 2018

B Fischer

4

1 reference

6 July 2018

M Maillard

5

1 reference

6 July 2018

A van Bergen

6

1 reference

6 July 2018

P J van Galen

7

1 reference

6 July 2018

Y Karton

8

1 reference

6 July 2018

language of work or name

English

0 references

publication date

1 May 1993

1 reference

6 July 2018

Journal of Medicinal Chemistry

published in

1 reference

6 July 2018

volume

36

1 reference

6 July 2018

issue

10

1 reference

6 July 2018

page(s)

1333-1342

1 reference

6 July 2018

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Species differences in structure-activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Structure-activity profile of a series of novel triazoloquinazoline adenosine antagonists

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Identification of the A2 adenosine receptor binding subunit by photoaffinity crosslinking

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Caffeine and theophylline analogues: correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

1,3,8-trisubstituted xanthines. Effects of substitution pattern upon adenosine receptor A1/A2 affinity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

2-aralkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

(E)-1,3-Dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Nucleosides and nucleotides. 107. 2-(Cycloalkylalkynyl)adenosines: adenosine A2 receptor agonists with potent antihypertensive effects

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Characterization of human striatal A2-adenosine receptors using radioligand binding and photoaffinity labeling

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Adenosine A1 and A2 receptors: structure--function relationships

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Adenosine-dopamine interactions in the brain

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5975975

Characterization of adenosine receptors in rat brain by (?)[3H]N6-phenylisopropyladenosine

10 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8496902

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Separation of solubilized A2 adenosine receptors of human platelets from non-receptor [3H]NECA binding sites by gel filtration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8496902

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A1 and A2 adenosine receptor regulation of erythropoietin production

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8496902

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM00062A005

1 reference

6 July 2018

PMC publication ID

5975975

1 reference

6 July 2018

PubMed publication ID

8496902

1 reference

6 July 2018