(Q42564287)

English

Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates.

scientific article published on January 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21211726%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21211726%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

quality control

0 references

nuclear protein quality control by the ubiquitin-proteasome system

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

Richard G Gardner

11

1 reference

Europe PubMed Central

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19 January 2020

Melissa N Locke

5

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19 January 2020

Lauren A Richardson

6

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19 January 2020

author name string

Joel C Rosenbaum

1

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19 January 2020

Eric K Fredrickson

2

1 reference

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19 January 2020

Michelle L Oeser

3

1 reference

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19 January 2020

Carrie M Garrett-Engele

4

1 reference

Europe PubMed Central

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19 January 2020

Zara W Nelson

7

1 reference

Europe PubMed Central

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19 January 2020

Elizabeth D Hetrick

8

1 reference

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19 January 2020

Thomas I Milac

9

1 reference

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19 January 2020

Daniel E Gottschling

10

1 reference

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19 January 2020

publication date

1 January 2011

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19 January 2020

1 reference

Europe PubMed Central

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19 January 2020

41

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19 January 2020

1

1 reference

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19 January 2020

93-106

1 reference

Europe PubMed Central

PMC publication ID

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19 January 2020

Proteolytic processing of tau.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

ANCHOR: web server for predicting protein binding regions in disordered proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Substrate binding site flexibility of the small heat shock protein molecular chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Intranuclear degradation of polyglutamine aggregates by the ubiquitin-proteasome system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

One step at a time: endoplasmic reticulum-associated degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

The unfoldomics decade: an update on intrinsically disordered proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Degradation of a cytosolic protein requires endoplasmic reticulum-associated degradation machinery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

The Jpred 3 secondary structure prediction server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications

1 reference

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28 May 2018

Using circular dichroism spectra to estimate protein secondary structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Abnormalities of the nucleus and nuclear inclusions in neurodegenerative disease: a work in progress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Assessing protein disorder and induced folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Nuclear aggresomes form by fusion of PML-associated aggregates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Degradation-mediated protein quality control in the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Hsp70 chaperones: cellular functions and molecular mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

The roles of proteolysis and nuclear localisation in the toxicity of the polyglutamine diseases. A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Functional transplantation of the sumoylation machinery into Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Probing protein structure by limited proteolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

CHIP: a link between the chaperone and proteasome systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Sir Antagonist 1 (San1) is a ubiquitin ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Analysis of the regulation of the molecular chaperone Hsp26 by temperature-induced dissociation: the N-terminal domail is important for oligomer assembly and the binding of unfolding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Intrinsically unstructured proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Crystal structure and assembly of a eukaryotic small heat shock protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Sequence complexity of disordered protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Why are "natively unfolded" proteins unstructured under physiologic conditions?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

28 May 2018

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

1 reference

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28 May 2018

Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast

1 reference

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28 May 2018

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

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28 May 2018

Reconstitution of Arabidopsis thaliana SUMO pathways in E. coli: functional evaluation of SUMO machinery proteins and mapping of SUMOylation sites by mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

16 August 2018

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042722

16 August 2018

Generation of SUMO-1 modified proteins in E. coli: towards understanding the biochemistry/structural biology of the SUMO-1 pathway

1 reference

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16 August 2018

Structural and functional implications of C-terminal regions of alpha-synuclein

1 reference

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16 August 2018

A domain in the N-terminal part of Hsp26 is essential for chaperone function and oligomerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/21211726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular chaperone-like properties of an unfolded protein, alpha(s)-casein

1 reference

https://pubmed.ncbi.nlm.nih.gov/21211726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLCEL.2010.12.004

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21211726%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PMC publication ID

1 reference

Europe PubMed Central

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19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21211726%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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