(Q42590553)

3 November 2017

Indoloquinone EO9: DNA interstrand cross-linking upon reduction by DT-diaphorase or xanthine oxidase (English)

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3 November 2017

Maliepaard M

1

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3 November 2017

Wolfs A

2

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3 November 2017

Groot SE

3

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3 November 2017

de Mol NJ

4

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3 November 2017

Janssen LH

5

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3 November 2017

language of work or name

English

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publication date

1 April 1995

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British Journal of Cancer

3 November 2017

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3 November 2017

71

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3 November 2017

836-839

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3 November 2017

4

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https://scigraph.springernature.com/pub.10.1038/bjc.1995.161

3 November 2017

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cites work

EO9: a novel bioreductive alkylating indoloquinone with preferential solid tumour activity and lack of bone marrow toxicity in preclinical models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

The changes of prooxidant and antioxidant enzyme activities in bovine leukemia virus-transformed cells. Their influence on quinone cytotoxicity

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of mitomycin C.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

One-electron transfer reactions in biochemical systems. VII. Two types of electron outlets in milk xanthine oxidase.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

Purification by cibacron blue F3GA dye affinity chromatography and comparison of NAD(P)H:quinone reductase (E.C.1.6.99.2) from rat liver cytosol and microsomes.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

In vitro activity of the novel indoloquinone EO-9 and the influence of pH on cytotoxicity.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

Structure-activity relationships for DT-diaphorase reduction of hypoxic cell directed agents: indoloquinones and diaziridinyl benzoquinones

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

28 May 2018

Bioreductive mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

DT-diaphorase activity correlates with sensitivity to the indoloquinone EO9 in mouse and human colon carcinomas

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033736

Reductive activation of potential antitumor bis(aziridinyl)benzoquinones by xanthine oxidase: competition between oxygen reduction and quinone reduction

28 May 2018

1 reference

12 December 2020

The Role of NAD(P)H: Quinone Reductase (EC 1.6.99.2, DT-Diaphorase) in the Reductive Bioactivation of the Novel Indoloquinone Antitumor Agent E09

1 reference

12 December 2020

High levels of expression of the NAD(P)H:Quinone oxidoreductase (NQO1) gene in tumor cells compared to normal cells of the same origin

1 reference

12 December 2020

The sensitivity of human tumour cells to quinone bioreductive drugs: what role for DT-diaphorase?

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12 December 2020

Bioreductive activation of mitomycin C by DT-diaphorase

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12 December 2020

Enhancement of xanthine dehydrogenase mediated mitomycin C metabolism by dicumarol

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12 December 2020

Reductive activation of potential antitumor mitosene compounds

1 reference

12 December 2020

Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P-450 reductase and xanthine oxidase

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1995.161

1 reference

3 November 2017

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3 November 2017

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