(Q42614760)

3 November 2017

title

A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population (English)

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3 November 2017

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11

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3 November 2017

10

P Emery

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Jane Worthington

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J Worthington

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Paul Wordsworth

6

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P Wordsworth

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3 November 2017

S L Mackie

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3 November 2017

J C Taylor

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3 November 2017

S G Martin

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3 November 2017

YEAR Consortium

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3 November 2017

UKRAG Consortium

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3 November 2017

S Steer

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A G Wilson

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3 November 2017

A W Morgan

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3 November 2017

publication date

1 September 2011

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3 November 2017

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3 November 2017

volume

13

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3 November 2017

issue

2

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3 November 2017

page(s)

120-128

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https://scigraph.springernature.com/pub.10.1038/gene.2011.60

3 November 2017

exact match

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cites work

Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.60

Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.60

T and B lymphocyte subsets in fenoprofen nephropathy

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.60

Quantifying the exact role of HLA-DRB1 alleles in susceptibility to inflammatory polyarthritis: results from a large, population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Anti-cyclic citrullinated peptide antibody is associated with radiographic erosion in rheumatoid arthritis independently of shared epitope status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Shared epitope and anti-cyclic citrullinated peptide antibodies: relationship with age at onset and duration of disease in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

The shared epitope hypothesis in rheumatoid arthritis: evaluation of alternative classification criteria in a large UK Caucasian cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Dwl4(DRBl*0404) is a Dw4-dependent risk factor for rheumatoid arthritis Rethinking the “shared epitope” hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

A majority of Brazilian patients with rheumatoid arthritis HLA-DRB1 alleles carry both the HLA-DRB1 shared epitope and anti-citrunillated peptide antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Opposing effects of the D70 mutation and the shared epitope in HLA-DR4 on disease activity and certain disease phenotypes in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

New classification of HLA-DRB1 alleles in rheumatoid arthritis susceptibility: a combined analysis of worldwide samples

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.60

Rheumatoid arthritis association at 6q23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

A "case control" study on the rôle of HLA DR4 in severe periodontitis and rapidly progressive periodontitis. Identification of types and subtypes using molecular biology (PCR.SSO).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Association between radiographic severity of rheumatoid arthritis and shared epitope alleles: differing mechanisms of susceptibility and protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated pr

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Independent association of rheumatoid factor and the HLA-DRB1 shared epitope with radiographic outcome in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

The role of the shared epitope in arthralgia with anti-cyclic citrullinated peptide antibodies (anti-CCP), and its effect on anti-CCP levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Associations between human leukocyte antigen, PTPN22, CTLA4 genotypes and rheumatoid arthritis phenotypes of autoantibody status, age at diagnosis and erosions in a large cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Predicting arthritis outcomes--what can be learned from the Leiden Early Arthritis Clinic?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Opposing effects of HLA-DRB1*13 alleles on the risk of developing anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

The HLA–DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

The HLA–DRB1 shared epitope alleles are primarily a risk factor for anti–cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Marked differences in fine specificity and isotype usage of the anti-citrullinated protein antibody in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

Rheumatoid arthritis: Relationship with HLA-D

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

7 January 2021

Associations between genetic factors, tobacco smoking and autoantibodies in familial and sporadic rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

7 January 2021

Genetic typing of patients with inflammatory arthritis at presentation can be used to predict outcome

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

7 January 2021

Compound heterozygosity for the shared epitope and the risk and severity of rheumatoid arthritis in extended pedigrees

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

7 January 2021

HLA-DQ-associated predisposition to and dominant HLA-DR-associated protection against rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

7 January 2021

Influence of shared epitope-negative HLA-DRB1 alleles on genetic susceptibility to rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

7 January 2021

DQCAR 113 and DQCAR 115 in combination with HLA-DRB1 alleles are significant markers of susceptibility to rheumatoid arthritis in the Korean population

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.60

7 January 2021

Identifiers

DOI

10.1038/GENE.2011.60

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Dimensions Publication ID

3 November 2017

1026198176

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1 reference