(Q42619127)

English

Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions.

scientific article published on May 2007

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scholarly article

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30 December 2019

Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions (English)

1 reference

Europe PubMed Central

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30 December 2019

Maria Virginia Soldovieri

1

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30 December 2019

Francesco Miceli

3

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30 December 2019

Lucio Annunziato

10

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30 December 2019

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Maria Roberta Cilio

2

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30 December 2019

Giulia Bellini

4

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30 December 2019

Emanuele Miraglia del Giudice

5

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30 December 2019

Pasqualina Castaldo

6

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30 December 2019

Ciria C Hernandez

7

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30 December 2019

Mark S Shapiro

8

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30 December 2019

Antonio Pascotto

9

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30 December 2019

Maurizio Taglialatela

11

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30 December 2019

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1 May 2007

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30 December 2019

Journal of Neuroscience

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30 December 2019

27

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30 December 2019

18

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30 December 2019

4919-4928

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30 December 2019

M-channel gating and simulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular Mg(2+) modulates slow gating transitions and the opening of Drosophila ether-à-Go-Go potassium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collapse of conductance is prevented by a glutamate residue conserved in voltage-dependent K(+) channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KCNQ2/KCNQ3 K+ channels and the molecular pathogenesis of epilepsy: implications for therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mg(2+) modulates voltage-dependent activation in ether-à-go-go potassium channels by binding between transmembrane segments S2 and S3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potassium channels: molecular defects, diseases, and therapeutic opportunities.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benign familial neonatal convulsions (BFNC) resulting from mutation of the KCNQ2 voltage sensor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ion channel variation causes epilepsies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benign familial neonatal convulsions caused by altered gating of KCNQ2/KCNQ3 potassium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-dependent modulation of hippocampal excitability by KCNQ-channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-ray structure of a voltage-dependent K+ channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KCNQ/M currents in sensory neurons: significance for pain therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potassium ion current in the squid giant axon: dynamic characteristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KCNQ2 and KCNQ3 potassium channel genes in benign familial neonatal convulsions: expansion of the functional and mutation spectrum

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

M channels containing KCNQ2 subunits modulate norepinephrine, aspartate, and GABA release from hippocampal nerve terminals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of permeant ions on voltage sensor function in the Kv2.1 potassium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-channel analysis of KCNQ K+ channels reveals the mechanism of augmentation by a cysteine-modifying reagent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effects of Maxipost (BMS-204352) and retigabine via activation of neuronal Kv7 channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic suppression of KCNQ channel currents enhances excitability of striatal medium spiny neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased subunit stability as a novel mechanism for potassium current impairment by a KCNQ2 C terminus mutation causing benign familial neonatal convulsions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage sensor conformations in the open and closed states in ROSETTA structural models of K(+) channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionic mechanisms of autorhythmic firing in rat cerebellar Golgi cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retigabine and flupirtine exert neuroprotective actions in organotypic hippocampal cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How does voltage open an ion channel?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidystonic effects of Kv7 (KCNQ) channel openers in the dt sz mutant, an animal model of primary paroxysmal dystonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrophobic substitution mutations in the S4 sequence alter voltage-dependent gating in Shaker K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimating the number of channels in patch recordings

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for hydrophobic residues in the voltage-dependent gating of Shaker K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage-clamp analysis of muscarinic excitation in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seizure characteristics in chromosome 20 benign familial neonatal convulsions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gating currents of the cloned delayed-rectifier K+ channel DRK1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular Mg2+ regulates activation of rat eag potassium channel.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of the S4 segment to gating charge in the Shaker K+ channel.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of M-current

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potassium channel mutation in neonatal human epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into the molecular and genetic mechanisms underlying idiopathic epilepsies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0580-07.2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17475800%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

release_2jqkratshfdrxpahk7juiwuh24

1 reference

https://api.fatcat.wiki/v0/release/2jqkratshfdrxpahk7juiwuh24

24 November 2022

based on heuristic

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PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17475800%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17475800%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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