(Q42626850)

4 November 2017

title

The reduced folate carrier in L1210 murine leukemia cells is a 58-kDa protein (English)

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4 November 2017

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R Zhao

1

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4 November 2017

F Gao

series ordinal

2

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4 November 2017

L Liu

series ordinal

3

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4 November 2017

I D Goldman

series ordinal

4

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4 November 2017

publication date

1 June 2000

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Biochimica et Biophysica Acta

4 November 2017

published in

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4 November 2017

volume

1466

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4 November 2017

issue

1-2

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4 November 2017

page(s)

7-10

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Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

4 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and directional orientation of the transporter w

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

Pattern of mutations that results in loss of reduced folate carrier function under antifolate selective pressure augmented by chemical mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

RFC-1 gene expression regulates folate absorption in mouse small intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

Photoaffinity analogues of methotrexate as folate antagonist binding probes. 2. Transport studies, photoaffinity labeling, and identification of the membrane carrier protein for methotrexate from murine L1210 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2800%2900190-5

10.1016/S0005-2736(00)00190-5

7 January 2021

Identifiers

DOI

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4 November 2017

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