(Q42630760)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22335895%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors (English)

1 reference

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23 January 2020

3

1 reference

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23 January 2020

Jonathan Higgins

11

1 reference

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23 January 2020

author name string

Gregory D Cuny

1

1 reference

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23 January 2020

Natalia P Ulyanova

2

1 reference

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23 January 2020

Ji-Feng Liu

4

1 reference

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23 January 2020

Xiangjie Lin

5

1 reference

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23 January 2020

Ken Auerbach

6

1 reference

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23 January 2020

Soumya S Ray

7

1 reference

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23 January 2020

Jun Xian

8

1 reference

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23 January 2020

Marcie A Glicksman

9

1 reference

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23 January 2020

Ross L Stein

10

1 reference

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23 January 2020

language of work or name

English

0 references

publication date

28 January 2012

1 reference

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Bioorganic & Medicinal Chemistry Letters

23 January 2020

number of pages

5

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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23 January 2020

volume

22

1 reference

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23 January 2020

issue

5

1 reference

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23 January 2020

page(s)

2015-2019

1 reference

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Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin

23 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Haspin: a newly discovered regulator of mitotic chromosome behavior.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Structure and functional characterization of the atypical human kinase haspin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Identification of small molecule inhibitors of the mitotic kinase haspin by high-throughput screening using a homogeneous time-resolved fluorescence resonance energy transfer assay

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

The selectivity of protein kinase inhibitors: a further update

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Structural and functional diversity of the microbial kinome

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Haspin-like proteins: a new family of evolutionarily conserved putative eukaryotic protein kinases

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Identification and characterization of a haploid germ cell-specific nuclear protein kinase (Haspin) in spermatid nuclei and its effects on somatic cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Isolation and characterization of cDNA clones specifically expressed in testicular germ cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

A general framework for inhibitor resistance in protein kinases.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Two histone marks establish the inner centromere and chromosome bi-orientation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288743

10.1016/J.BMCL.2012.01.028

16 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22335895%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22335895%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

22335895

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22335895%20AND%20SRC:MED&resulttype=core&format=json