(Q42631272)

4 November 2017

title

Homology modeling of NR2B modulatory domain of NMDA receptor and analysis of ifenprodil binding (English)

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4 November 2017

1

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2

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4

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6

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4 November 2017

Thomas Steinbrecher

3

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4 November 2017

Alessia Bertamino

series ordinal

5

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4 November 2017

David A Case

series ordinal

7

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4 November 2017

publication date

1 October 2007

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4 November 2017

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4 November 2017

volume

2

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4 November 2017

issue

10

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4 November 2017

page(s)

1498-1510

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Structure and function of glutamate receptor ion channels

4 November 2017

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Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington disease

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Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor-mediated synaptic currents in a mouse model of Huntington disease

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Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia.

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Evidence for a tetrameric structure of recombinant NMDA receptors.

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Identification of molecular determinants that are important in the assembly of N-methyl-D-aspartate receptors

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7 January 2021

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

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Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit.

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7 January 2021

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

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7 January 2021

Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors.

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7 January 2021

Identification of critical residues in the amino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket

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7 January 2021

The micromolar zinc-binding domain on the NMDA receptor subunit NR2B.

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7 January 2021

How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors

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7 January 2021

Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity

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7 January 2021

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

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7 January 2021

Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor

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7 January 2021

A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein

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7 January 2021

Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone

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7 January 2021

Antagonist properties of the stereoisomers of ifenprodil at NR1A/NR2A and NR1A/NR2B subtypes of the NMDA receptor expressed in Xenopus oocytes.

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7 January 2021

Separation of .alpha.1-adrenergic and N-methyl-D-aspartate antagonist activity in a series of ifenprodil compounds

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7 January 2021

(1S,2S)-1-(4-Hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: A Potent New Neuroprotectant Which Blocks N-Methyl-D-Aspartate Responses

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

NR2B selective NMDA antagonists: the evolution of the ifenprodil-type pharmacophore

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7 January 2021

Structure-activity relationships for a series of bis(phenylalkyl)amines: potent subtype-selective inhibitors of N-methyl-D-aspartate receptors.

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7 January 2021

Recent advances in the development of NR2B subtype-selective NMDA receptor antagonists

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7 January 2021

Theory and applications of the generalized Born solvation model in macromolecular simulations

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7 January 2021

Comparative protein structure modeling of genes and genomes

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7 January 2021

Comparative protein modelling by satisfaction of spatial restraints

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7 January 2021

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

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7 January 2021

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

Automated docking of flexible ligands: applications of AutoDock

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

Development and testing of a general amber force field

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

Comparison of simple potential functions for simulating liquid water

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

Molecular dynamics with coupling to an external bath

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

Ordered water and ligand mobility in the HIV-1 integrase-5CITEP complex: a molecular dynamics study.

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https://api.crossref.org/works/10.1002%2FCMDC.200700091

7 January 2021

Identifiers

DOI

10.1002/CMDC.200700091

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4 November 2017

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