(Q42644430)

English

Nine hydrophobic side chains are key determinants of the thermodynamic stability and oligomerization status of tumour suppressor p53 tetramerization domain

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

4 November 2017

Nine hydrophobic side chains are key determinants of the thermodynamic stability and oligomerization status of tumour suppressor p53 tetramerization domain (English)

1 reference

Europe PubMed Central

4 November 2017

1 reference

based on heuristic

inferred from title

2

object named as

Fersht AR

1 reference

Europe PubMed Central

4 November 2017

author name string

Mateu MG

1

1 reference

Europe PubMed Central

4 November 2017

language of work or name

0 references

publication date

1 May 1998

1 reference

Europe PubMed Central

4 November 2017

The EMBO Journal

1 reference

Europe PubMed Central

4 November 2017

17

1 reference

Europe PubMed Central

4 November 2017

2748-2758

1 reference

Europe PubMed Central

4 November 2017

10

1 reference

Europe PubMed Central

4 November 2017

Hydrophobic side-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

p53, the cellular gatekeeper for growth and division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Therapeutic targeting of the p53 tumor suppressor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Equilibrium dissociation and unfolding of the dimeric human papillomavirus strain-16 E2 DNA-binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Structural aspects of the p53 protein in relation to gene evolution: a second look.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

p53: puzzle and paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

New insights into p53 function from structural studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Forces contributing to the conformational stability of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Structural and genetic analysis of the folding and function of T4 lysozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Specific sequences from the carboxyl terminus of human p53 gene product form anti-parallel tetramers in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

p53 domains: structure, oligomerization, and transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

p53 and Rb: their cellular roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Refined solution structure of the oligomerization domain of the tumour suppressor p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Solution structure of the tetrameric minimum transforming domain of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Studies on protein stability with T4 lysozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Conformational stability of dimeric proteins: quantitative studies by equilibrium denaturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian cell assays in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

RASMOL: biomolecular graphics for all

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Determination and analysis of urea and guanidine hydrochloride denaturation curves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Equilibrium dissociation and unfolding of the Arc repressor dimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

A simple method for site-directed mutagenesis using the polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Calculation of protein extinction coefficients from amino acid sequence data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Contributions of the large hydrophobic amino acids to the stability of staphylococcal nuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

p53 mutations in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Contributions of the polar, uncharged amino acids to the stability of staphylococcal nuclease: evidence for mutational effects on the free energy of the denatured state.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

The folding of an enzyme. II. Substructure of barnase and the contribution of different interactions to protein stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Definition of a consensus binding site for p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

27 May 2018

Protein stability as a function of denaturant concentration: the thermal stability of barnase in the presence of urea.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170615

16 August 2018

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamic analysis of the structural stability of the tetrameric oligomerization domain of p53 tumor suppressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dominating effect of mutant p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein stability effects of a complete set of alanine substitutions in Arc repressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oligomerization domain of p53: Crystal structure of the trigonal form

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamics of denaturation of mutants of barnase with disulfide crosslinks

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro structure-function analysis of the beta-strand 326-333 of human p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An engineered four-stranded coiled coil substitutes for the tetramerization domain of wild-type p53 and alleviates transdominant inhibition by tumor-derived p53 mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/9582268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/17.10.2748

1 reference

Europe PubMed Central

4 November 2017

1 reference

Europe PubMed Central

4 November 2017

1 reference

Europe PubMed Central

4 November 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42644430&oldid=1964396508"