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An Inhibitor of PIDDosome Formation.
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PMC publication ID
4458193
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25936804%20AND%20SRC:MED&resulttype=core&format=json
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7 March 2020
title
An Inhibitor of PIDDosome Formation
(English)
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PMC publication ID
4458193
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7 March 2020
author
Hongdau Liu
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3
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7 March 2020
Yogesh Gupta
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4
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4458193
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7 March 2020
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Ruth Thompson
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7 March 2020
Richa B Shah
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2
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7 March 2020
Kiyohiro Ando
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5
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7 March 2020
Aneel K Aggarwal
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6
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4458193
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7 March 2020
Samuel Sidi
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7
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7 March 2020
publication date
30 April 2015
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7 March 2020
published in
Molecular Cell
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4458193
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7 March 2020
volume
58
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7 March 2020
issue
5
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4458193
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7 March 2020
page(s)
767-779
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4458193
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25936804%20AND%20SRC:MED&resulttype=core&format=json
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7 March 2020
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Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome
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27 May 2018
PIDD mediates and stabilizes the interaction between RAIDD and caspase-2 for the PIDDosome assembly
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PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling
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Neuronal caspase 2 activity and function requires RAIDD, but not PIDD
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Tumor-suppressing function of caspase-2 requires catalytic site Cys-320 and site Ser-139 in mice
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P53-induced protein with a death domain (PIDD): master of puppets?
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The PIDDosome, DNA-damage-induced apoptosis and beyond
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ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress
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Structure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1
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The PIDDosome mediates delayed death of hippocampal CA1 neurons after transient global cerebral ischemia in rats
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DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore
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DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis
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Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex
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Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway
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BubR1 is involved in regulation of DNA damage responses
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27 May 2018
PIDD mediates NF-kappaB activation in response to DNA damage
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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27 May 2018
Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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27 May 2018
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors
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27 May 2018
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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27 May 2018
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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27 May 2018
Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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27 May 2018
LRDD, a novel leucine rich repeat and death domain containing protein
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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27 May 2018
RAIDD is a new 'death' adaptor molecule
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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27 May 2018
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
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27 May 2018
Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20.
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16 August 2018
Integration of kinase and phosphatase activities by BUBR1 ensures formation of stable kinetochore-microtubule attachments.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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16 August 2018
Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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16 August 2018
Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
retrieved
16 August 2018
Chk1 is required for spindle checkpoint function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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16 August 2018
Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
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16 August 2018
The Drosophila Grp/Chk1 DNA damage checkpoint controls entry into anaphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4458193
retrieved
16 August 2018
DNA damage- and stress-induced apoptosis occurs independently of PIDD
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25936804
retrieved
12 December 2020
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inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.MOLCEL.2015.03.034
1 reference
stated in
Europe PubMed Central
PMC publication ID
4458193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25936804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PMC publication ID
4458193
1 reference
stated in
Europe PubMed Central
PMC publication ID
4458193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25936804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PubMed publication ID
25936804
1 reference
stated in
Europe PubMed Central
PMC publication ID
4458193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25936804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
ResearchGate publication ID
275836105
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