(Q42651331)

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Catalytic activation of human glucokinase by substrate binding: residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions

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Europe PubMed Central

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4 November 2017

Catalytic activation of human glucokinase by substrate binding: residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions (English)

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Europe PubMed Central

PubMed publication ID

4 November 2017

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Pål R Njølstad

4

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Pål R Njølstad

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Europe PubMed Central

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4 November 2017

3

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Oddmund Søvik

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Europe PubMed Central

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4 November 2017

Lise Bjørkhaug Gundersen

2

object named as

Lise Bjørkhaug

1 reference

Europe PubMed Central

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4 November 2017

Torgeir Flatmark

5

object named as

Torgeir Flatmark

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Europe PubMed Central

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4 November 2017

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Janne Molnes

1

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4 November 2017

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publication date

7 April 2008

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Europe PubMed Central

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4 November 2017

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Europe PubMed Central

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4 November 2017

275

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Europe PubMed Central

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4 November 2017

10

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Europe PubMed Central

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4 November 2017

2467-2481

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Europe PubMed Central

PubMed publication ID

4 November 2017

Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Human liver glucokinase gene: cloning and sequence determination of two alternatively spliced cDNAs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Permanent neonatal diabetes caused by glucokinase deficiency: inborn error of the glucose-insulin signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Neonatal diabetes mellitus due to complete glucokinase deficiency

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Mechanistic origin of the sigmoidal rate behaviour of rat liver hexokinase D ('glucokinase').

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Kinetic evidence for a 'mnemonical' mechanism for rat liver glucokinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

CUPSAT: prediction of protein stability upon point mutations.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Analysis of the cooperativity of human beta-cell glucokinase through the stimulatory effect of glucose on fructose phosphorylation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Coupling between catalytic site and collective dynamics: a requirement for mechanochemical activity of enzymes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

oGNM: online computation of structural dynamics using the Gaussian Network Model

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Conformational transition pathway in the allosteric process of human glucokinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Structural mechanisms for domain movements in proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Structure-function analysis of the alpha5 and the alpha13 helices of human glucokinase: description of two novel activating mutations.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Heterogeneity in disease severity in a family with a novel G68V GCK activating mutation causing persistent hyperinsulinaemic hypoglycaemia of infancy.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Calculation of protein extinction coefficients from amino acid sequence data

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Quantitative analysis of protein far UV circular dichroism spectra by neural networks

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

A database of macromolecular motions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

The morph server: a standardized system for analyzing and visualizing macromolecular motions in a database framework

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Helix Interaction Tool (HIT): a web-based tool for analysis of helix-helix interactions in proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06391.X

21 January 2018

Identifiers

10.1111/J.1742-4658.2008.06391.X

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

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