(Q42657377)

English

The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity

scientific article published on 28 June 2017

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity (English)

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

Fiona Thistlethwaite

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Dominic G Rothwell

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

David E Gilham

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ryan D Guest

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Manon Pillai

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Deborah J Burt

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Andrea J Byatte

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Natalia Kirillova

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Juan W Valle

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Surinder K Sharma

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Kerry A Chester

11

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Nigel B Westwood

12

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Sarah E R Halford

13

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Stephen Nabarro

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Susan Wan

15

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Eric Austin

16

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Robert E Hawkins

17

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

publication date

28 June 2017

1 reference

Europe PubMed Central

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4 November 2017

Cancer Immunology, Immunotherapy

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

66

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1425-1436

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

copyright license

Creative Commons Attribution 4.0 International

28 June 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Driving gene-engineered T cell immunotherapy of cancer

1 reference

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27 May 2018

Prospects for gene-engineered T cell immunotherapy for solid cancers.

1 reference

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27 May 2018

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

CAR-T Cell Therapy for Lymphoma.

1 reference

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27 May 2018

Adoptive Cell Therapy--Tumor-Infiltrating Lymphocytes, T-Cell Receptors, and Chimeric Antigen Receptors.

1 reference

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27 May 2018

Phase I Hepatic Immunotherapy for Metastases Study of Intra-Arterial Chimeric Antigen Receptor-Modified T-cell Therapy for CEA+ Liver Metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Adoptive cell transfer as personalized immunotherapy for human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Chimeric antigen receptor T cells for sustained remissions in leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

CD28z CARs and armored CARs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Definition and application of good manufacturing process-compliant production of CEA-specific chimeric antigen receptor expressing T-cells for phase I/II clinical trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Immune responses to transgene and retroviral vector in patients treated with ex vivo–engineered T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Building better chimeric antigen receptors for adoptive T cell therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

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Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

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27 May 2018

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

1 reference

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

T lymphocytes isolated from patients with advanced colorectal cancer are suitable for gene immunotherapy approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5645435

27 May 2018

Primary polyclonal human T lymphocytes targeted to carcino-embryonic antigens and neural cell adhesion molecule tumor antigens by CD3zeta-based chimeric immune receptors.

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27 May 2018

Carcinoembryonic antigen as a target for therapeutic anticancer vaccines: a review

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Clinical applications of phage-derived sFvs and sFv fusion proteins

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Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma

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Expression of carcinoembryonic antigen and related genes in lung and gastrointestinal cancers

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16 August 2018

Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and I

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Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

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https://pubmed.ncbi.nlm.nih.gov/28660319

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based on heuristic

inferred from PubMed ID database lookup

T cell activation by antibody-like immunoreceptors: the position of the binding epitope within the target molecule determines the efficiency of activation of redirected T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28660319

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Ultrastructural localization of carcinoembryonic antigen in normal intestine and colon cancer: abnormal distribution of CEA on the surfaces of colon cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28660319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00262-017-2034-7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28660319%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

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