(Q42675291)

English

Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state

scientific article published on June 1999

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scholarly article

1 reference

Europe PubMed Central

4 November 2017

Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state (English)

1 reference

Europe PubMed Central

4 November 2017

prion protein family

0 references

author name string

Horiuchi M

1

1 reference

Europe PubMed Central

4 November 2017

Caughey B

2

1 reference

Europe PubMed Central

4 November 2017

language of work or name

0 references

publication date

1 June 1999

1 reference

Europe PubMed Central

4 November 2017

The EMBO Journal

1 reference

Europe PubMed Central

4 November 2017

18

1 reference

Europe PubMed Central

4 November 2017

12

1 reference

Europe PubMed Central

4 November 2017

3193-3203

1 reference

Europe PubMed Central

4 November 2017

Prion rods contain small amounts of two host sphingolipids as revealed by thin-layer chromatography and mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Overexpression of nonconvertible PrPc delta114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild-type PrP(Sc) accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Complementary hydropathy identifies a cellular prion protein receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Chaperone-supervised conversion of prion protein to its protease-resistant form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Molecular properties of complexes formed between the prion protein and synthetic peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Molecular assessment of the potential transmissibilities of BSE and scrapie to humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Prion protein NMR structure and species barrier for prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Identification of candidate proteins binding to prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Recombinant scrapie-like prion protein of 106 amino acids is soluble

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Partial unfolding and refolding of scrapie-associated prion protein: evidence for a critical 16-kDa C-terminal domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

NMR structure of the mouse prion protein domain PrP(121-231)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Mice devoid of PrP are resistant to scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Non-genetic propagation of strain-specific properties of scrapie prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Binding of the protease-sensitive form of PrP (prion protein) to sulfated glycosaminoglycan and congo red [corrected]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Separation and properties of cellular and scrapie prion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

A cellular gene encodes scrapie PrP 27-30 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Sulfated glycosaminoglycans in amyloid plaques of prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Three-dimensional structure of a complex of antibody with influenza virus neuraminidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Molecular location of a species-specific epitope on the hamster scrapie agent protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Molecular biology of prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Evidence for synthesis of scrapie prion proteins in the endocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

Chimeric prion protein expression in cultured cells and transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

27 May 2018

NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

16 August 2018

Normal host prion protein necessary for scrapie-induced neurotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

16 August 2018

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

16 August 2018

Cell-free formation of protease-resistant prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

16 August 2018

Truncated forms of the human prion protein in normal brain and in prion diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

16 August 2018

Identification of cellular proteins binding to the scrapie prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171400

16 August 2018

The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparin-like molecules bind differentially to prion-proteins and change their intracellular metabolic fate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/18.12.3193

1 reference

Europe PubMed Central

4 November 2017

release_cksg65m745djjiwiwhp6c6lml4

1 reference

https://api.fatcat.wiki/v0/release/cksg65m745djjiwiwhp6c6lml4

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

4 November 2017

1 reference

Europe PubMed Central

4 November 2017

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