(Q42683184)

English

Twinkle, the mitochondrial replicative DNA helicase, is widespread in the eukaryotic radiation and may also be the mitochondrial DNA primase in most eukaryotes

scientific article published on 11 April 2006

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scholarly article

1 reference

Europe PubMed Central

4 November 2017

Twinkle, the mitochondrial replicative DNA helicase, is widespread in the eukaryotic radiation and may also be the mitochondrial DNA primase in most eukaryotes (English)

1 reference

Europe PubMed Central

4 November 2017

mitochondrial DNA

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based on heuristic

inferred from title

2

object named as

Michael W Gray

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Europe PubMed Central

4 November 2017

author name string

Timothy E Shutt

1

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Europe PubMed Central

4 November 2017

publication date

11 April 2006

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Europe PubMed Central

4 November 2017

Journal of Molecular Evolution

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Europe PubMed Central

4 November 2017

62

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Europe PubMed Central

4 November 2017

5

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Europe PubMed Central

4 November 2017

588-599

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Europe PubMed Central

4 November 2017

https://scigraph.springernature.com/pub.10.1007/s00239-005-0162-8

0 references

Sensory ataxic neuropathy due to a novel C10Orf2 mutation with probable germline mosaicism

1 reference

https://api.crossref.org/works/10.1007%2FS00239-005-0162-8

21 January 2018

Sequences homologous to yeast mitochondrial and bacteriophage T3 and T7 RNA polymerases are widespread throughout the eukaryotic lineage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A trypanosome mitochondrial RNA polymerase is required for transcription and replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The DNA helicase, Hmi1p, is transported into mitochondria by a C-terminal cleavable targeting signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kingdom-level phylogeny of eukaryotes based on combined protein data

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TWINKLE Has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unusual organization of a developmentally regulated mitochondrial RNA polymerase (TBMTRNAP) gene in Trypanosoma brucei

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intron "sliding" and the diversity of intron positions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nucleariid amoebae: more protists at the animal-fungal boundary

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the presence of DNA primase in mitochondria of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIF1: a DNA helicase in yeast mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

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Cytoskeletal organization, phylogenetic affinities and systematics in the contentious taxon Excavata (Eukaryota).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanism for all polymerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bacterial replicative helicase DnaB evolved from a RecA duplication

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution of a minimal mtDNA replisome in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential loss and gain of introns in 3' portions of genes suggests a reverse-transcription mechanism of intron insertion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Closest Unicellular Relatives of Animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

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Multiple sequence alignment with the Clustal series of programs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The twilight of Heliozoa and rise of Rhizaria, an emerging supergroup of amoeboid eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel Twinkle gene mutation in autosomal dominant progressive external ophthalmoplegia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C- to N-terminal translocation of preproteins into mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acidic residues in the nucleotide-binding site of the bacteriophage T7 DNA primase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The real 'kingdoms' of eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The linker region between the helicase and primase domains of the bacteriophage T7 gene 4 protein is critical for hexamer formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plastid evolution: origins, diversity, trends

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modular architecture of the bacteriophage T7 primase couples RNA primer synthesis to DNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Only six kingdoms of life

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of a DNA primase from human mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct physical interaction between DnaG primase and DnaB helicase of Escherichia coli is necessary for optimal synthesis of primer RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The crystal structure of the bifunctional primase-helicase of bacteriophage T7

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization and evolution of bacterial and bacteriophage primase-helicase systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New features of mitochondrial DNA replication system in yeast and man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of kinetoplast DNA: an update for the new millennium

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restriction-site PCR: a direct method of unknown sequence retrieval adjacent to a known locus by using universal primers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One RNA polymerase serving two genomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A DNA helicase required for maintenance of the functional mitochondrial genome in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of DNA polymerase families: evidences for multiple gene exchange between cellular and viral proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the monophyly of chromalveolates using a six-protein phylogeny of eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Haemophilus influenzae dnaG sequence and conserved bacterial primase motifs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DnaG interacts with a linker region that joins the N- and C-domains of DnaB and induces the formation of 3-fold symmetric rings

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The plastidic DNA replication enzyme complex of Plasmodium falciparum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bacterial helicase-primase interaction: a common structural/functional module.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential lysine residues in the RNA polymerase domain of the gene 4 primase-helicase of bacteriophage T7.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Complex of the Bacteriophage T7 Primase-Helicase and DNA Polymerase Directs Primer Utilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mitochondrial DNA primase from the trypanosomatid Crithidia fasciculata

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the zinc motif in sequence recognition by DNA primases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of autosomal dominant progressive external ophthalmoplegia to a 7-cM critical region on 10q24

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Digenic progressive external ophthalmoplegia in a sporadic patient: recessive mutations in POLG and C10orf2/Twinkle

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a domain of Escherichia coli primase required for functional interaction with the DnaB helicase at the replication fork

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural classification of zinc fingers: survey and summary

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phylogeny of lobose amoebae based on actin and small-subunit ribosomal RNA genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid acquisition of unknown DNA sequence adjacent to a known segment by multiplex restriction site PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resolution and purification of free primase activity from the DNA primase-polymerase alpha complex of HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Import of yeast mitochondrial transcription factor (Mtf1p) via a nonconventional pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A refined localization of the mitochondrial DNA primase in Crithidia fasciculata

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and molecular features of adPEO due to mutations in the Twinkle gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00239-005-0162-8

1 reference

Europe PubMed Central

4 November 2017

1 reference

Europe PubMed Central

4 November 2017

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