(Q42691597)

English

Three-dimensional structures of the mammalian multidrug resistance P-glycoprotein demonstrate major conformational changes in the transmembrane domains upon nucleotide binding

scientific article published on 25 December 2002

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 November 2017

Three-dimensional structures of the mammalian multidrug resistance P-glycoprotein demonstrate major conformational changes in the transmembrane domains upon nucleotide binding (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

transmembrane protein

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multiple drug resistance

1 reference

based on heuristic

inferred from title

Richard Callaghan

3

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

author name string

Mark F Rosenberg

1

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

Alhaji Bukar Kamis

2

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Europe PubMed Central

PubMed publication ID

4 November 2017

Christopher F Higgins

4

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Europe PubMed Central

PubMed publication ID

4 November 2017

language of work or name

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publication date

25 December 2002

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Europe PubMed Central

PubMed publication ID

4 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

4 November 2017

278

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Europe PubMed Central

PubMed publication ID

4 November 2017

10

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Europe PubMed Central

PubMed publication ID

4 November 2017

8294-8299

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

The Escherichia coli ATP-binding cassette (ABC) proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

ABC Transporters: From Microorganisms to Man

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Structure and association of ATP-binding cassette transporter nucleotide-binding domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Crystal structure of the ATP-binding subunit of an ABC transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

The multi-drug resistance reversal agent SR33557 and modulation of vinca alkaloid binding to P-glycoprotein by an allosteric interaction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

The vinblastine binding site adopts high- and low-affinity conformations during a transport cycle of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Analysis of MDR1 P-glycoprotein conformational changes in permeabilized cells using differential immunoreactivity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Conformational changes of P-glycoprotein by nucleotide binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Ligand-mediated tertiary structure changes of reconstituted P-glycoprotein. A tryptophan fluorescence quenching analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Three-dimensional map of the plasma membrane H+-ATPase in the open conformation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Surface crystallisation of the plasma membrane H+-ATPase on a carbon support film for electron crystallography

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

MRC image processing programs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Three-dimensional structure determination by electron microscopy of two-dimensional crystals.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Human Erythrocyte Catalase: 2-D Crystal Nucleation and Production of Multiple Crystal Forms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

The location of plastocyanin in vascular plant photosystem I.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Projection structure of P-glycoprotein by electron microscopy. Evidence for a closed conformation of the nucleotide binding domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Is the multidrug transporter a flippase?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Calcein accumulation as a fluorometric functional assay of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Assessment of resolution in biological electron crystallography

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Inhibition of Oxidative Cross-linking between Engineered Cysteine Residues at Positions 332 in Predicted Transmembrane Segments (TM) 6 and 975 in Predicted TM12 of Human P-glycoprotein by Drug Substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211758200

21 January 2018

Identifiers

10.1074/JBC.M211758200

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 November 2017

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