(Q57976949)

English

Inhibition of Oxidative Cross-linking between Engineered Cysteine Residues at Positions 332 in Predicted Transmembrane Segments (TM) 6 and 975 in Predicted TM12 of Human P-glycoprotein by Drug Substrates

scientific article published in Journal of Biological Chemistry

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910331%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Inhibition of oxidative cross-linking between engineered cysteine residues at positions 332 in predicted transmembrane segments (TM) 6 and 975 in predicted TM12 of human P-glycoprotein by drug substrates (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910331%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

transmembrane protein

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1

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21 October 2019

author name string

D M Clarke

2

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21 October 2019

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1 November 1996

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21 October 2019

Journal of Biological Chemistry

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21 October 2019

271

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21 October 2019

27482-27487

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21 October 2019

44

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21 October 2019

The biochemistry of P-glycoprotein-mediated multidrug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

P-glycoprotein, multidrug resistance and tumor progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Multidrug resistance and the role of P-glycoprotein knockout mice

1 reference

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21 January 2018

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

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21 January 2018

The ABC of channel regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Helix packing of lactose permease in Escherichia coli studied by site-directed chemical cleavage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Distance determination in proteins using designed metal ion binding sites and site-directed spin labeling: application to the lactose permease of Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Membrane topology of a cysteine-less mutant of human P-glycoprotein

1 reference

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21 January 2018

Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Disulfide cross-linking studies of the transmembrane regions of the aspartate sensory receptor of Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

P-glycoprotein. Associations between domains and between domains and molecular chaperones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Global flexibility in a sensory receptor: a site-directed cross-linking approach.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Lock on/off disulfides identify the transmembrane signaling helix of the aspartate receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Determination of transmembrane protein structure by disulfide cross-linking: the Escherichia coli Tar receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

A general method for mapping tertiary contacts between amino acid residues in membrane-embedded proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Expression of the human multidrug transporter in insect cells by a recombinant baculovirus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Interaction of forskolin with the P-glycoprotein multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Mutational Analysis of the Predicted First Transmembrane Segment of Each Homologous Half of Human P-glycoprotein Suggests That They Are Symmetrically Arranged in the Membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Monoclonal antibodies to the Ca2+ + Mg2+-dependent ATPase of sarcoplasmic reticulum identify polymorphic forms of the enzyme and indicate the presence in the enzyme of a classical high-affinity Ca2+ binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

A method for the determination of inorganic phosphate in the presence of labile organic phosphate and high concentrations of protein: application to lens ATPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27482

21 January 2018

Identifiers

10.1074/JBC.271.44.27482

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910331%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910331%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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