(Q42694332)

1 July 2019

title

Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity (English)

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1 July 2019

glycogen catabolic process

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Aloysius J. Klingelhutz

series ordinal

2

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1 July 2019

author name string

Gopi S Gadupudi

series ordinal

1

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1 July 2019

Larry W Robertson

series ordinal

3

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1 July 2019

language of work or name

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23 August 2016

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1 July 2019

Chemical Research in Toxicology

published in

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1 July 2019

volume

29

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1 July 2019

issue

9

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1 July 2019

page(s)

1504-1509

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1 July 2019

describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6298789/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Regulation of glucose production by the liver

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The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

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12 December 2020

CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

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12 December 2020

Transcriptional regulation by the phosphorylation-dependent factor CREB

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12 December 2020

Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB.

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12 December 2020

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

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12 December 2020

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

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The key role of anaplerosis and cataplerosis for citric acid cycle function.

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DNA binding and protein interactions of the AHR/ARNT heterodimer that facilitate gene activation

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Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

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Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action

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Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis

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Monofluorinated analogues of polychlorinated biphenyls (F-PCBs): Synthesis using the Suzuki-coupling, characterization, specific properties and intended use

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12 December 2020

NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).

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Association of a polychlorinated dibenzo-p-dioxin, a polychlorinated biphenyl, and DDT with diabetes in the 1999–2002 National Health and Nutrition Examination Survey

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Suppression of peroxisomal enzyme activities and cytochrome P450 4A isozyme expression by congeneric polybrominated and polychlorinated biphenyls

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Reduced activities of key enzymes of gluconeogenesis as possible cause of acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats

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The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

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Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia

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Polychlorinated biphenyls, lead, and mercury are associated with liver disease in American adults: NHANES 2003-2004.

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CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

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Polychlorinated biphenyl (PCB) exposure and diabetes: results from the Anniston Community Health Survey.

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N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents

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Polybrominated diphenyl ethers alter hepatic phosphoenolpyruvate carboxykinase enzyme kinetics in male Wistar rats: implications for lipid and glucose metabolism.

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12 December 2020

CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesis

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12 December 2020

Energy metabolism in the liver

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PCB126 inhibits adipogenesis of human preadipocytes

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Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.

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In pursuit of genes of glucose metabolism

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12 December 2020

PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats

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Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene

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12 December 2020

Binding of polychlorinated biphenyls classified as either phenobarbitone-, 3-methylcholanthrene- or mixed-type inducers to cytosolic Ah receptor

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Subchronic/chronic toxicity of a mixture of four chlorinated dibenzo-p-dioxins in rats. II. Biochemical effects.

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12 December 2020

10.1021/ACS.CHEMRESTOX.6B00172

Identifiers

DOI

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1 July 2019

PMC publication ID

6298789

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1 July 2019

PubMed publication ID

27509375

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1 July 2019