(Q42700824)

English

Linking genotype and phenotype of Saccharomyces cerevisiae strains reveals metabolic engineering targets and leads to triterpene hyper-producers.

scientific article published on 18 March 2011

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scholarly article

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26 January 2020

Linking genotype and phenotype of Saccharomyces cerevisiae strains reveals metabolic engineering targets and leads to triterpene hyper-producers (English)

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26 January 2020

Saccharomyces cerevisiae

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based on heuristic

inferred from title

6

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26 January 2020

D B R K Gupta Udatha

2

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26 January 2020

8

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26 January 2020

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Karina M Madsen

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26 January 2020

Saori Semba

3

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26 January 2020

Jose M Otero

4

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26 January 2020

Peter Koetter

5

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26 January 2020

Yutaka Ebizuka

7

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26 January 2020

Gianni Panagiotou

9

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26 January 2020

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18 March 2011

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26 January 2020

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26 January 2020

6

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26 January 2020

3

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26 January 2020

e14763

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26 January 2020

copyright license

Creative Commons Attribution 4.0 International

18 March 2011

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April 2022 Public Data File from Crossref

copyright status

0 references

Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications

1 reference

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Structural and functional restraints on the occurrence of single amino acid variations in human proteins

1 reference

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Stability effects of mutations and protein evolvability

1 reference

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In the light of directed evolution: pathways of adaptive protein evolution

1 reference

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Structure of the Ternary Complex of Phosphomevalonate Kinase: The Enzyme and Its Family

1 reference

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Inferring stabilizing mutations from protein phylogenies: application to influenza hemagglutinin

1 reference

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27 May 2018

The Protein Model Portal

1 reference

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Searching protein structure databases with DaliLite v.3

1 reference

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Metabolic engineering of microorganisms: general strategies and drug production

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Prediction by graph theoretic measures of structural effects in proteins arising from non-synonymous single nucleotide polymorphisms

1 reference

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A three-state prediction of single point mutations on protein stability changes.

1 reference

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Cloning, solubilization, and characterization of squalene synthase from Thermosynechococcus elongatus BP-1

1 reference

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Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms

1 reference

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Application of functional genomics to pathway optimization for increased isoprenoid production.

1 reference

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Engineering triterpene production in Saccharomyces cerevisiae-beta-amyrin synthase from Artemisia annua

1 reference

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Combinatorial engineering of microbes for optimizing cellular phenotype

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Redirection of flux through the FPP branch-point in Saccharomyces cerevisiae by down-regulating squalene synthase

1 reference

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Modeling backbone flexibility improves protein stability estimation.

1 reference

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Prediction of protein stability upon point mutations

1 reference

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Protein stability imposes limits on organism complexity and speed of molecular evolution

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Clustal W and Clustal X version 2.0

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Statistical analysis of physical-chemical properties and prediction of protein-protein interfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060802

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ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060802

27 May 2018

Expanding the metabolic engineering toolbox: more options to engineer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060802

27 May 2018

Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060802

27 May 2018

Biosynthesis and engineering of isoprenoid small molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060802

27 May 2018

Food components that reduce cholesterol absorption

1 reference

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27 May 2018

CUPSAT: prediction of protein stability upon point mutations.

1 reference

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CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues

1 reference

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Production of the antimalarial drug precursor artemisinic acid in engineered yeast

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Loss of protein structure stability as a major causative factor in monogenic disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060802

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I-Mutant2.0: predicting stability changes upon mutation from the protein sequence or structure

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Thermodynamic prediction of protein neutrality

1 reference

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SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs

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Inter-residue interactions in protein folding and stability

1 reference

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SuperPose: a simple server for sophisticated structural superposition

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HFA1 encoding an organelle-specific acetyl-CoA carboxylase controls mitochondrial fatty acid synthesis in Saccharomyces cerevisiae.

1 reference

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Metabolic engineering for drug discovery and development

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Announcing the worldwide Protein Data Bank

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Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase

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Nonorthologous gene displacement of phosphomevalonate kinase.

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Topological Determinants of Protein Domain Swapping

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Many things from one

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based on heuristic

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21445244

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based on heuristic

inferred from PubMed ID database lookup

Effect of benzoic acid on metabolic fluxes in yeasts: a continuous-culture study on the regulation of respiration and alcoholic fermentation

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0014763

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21445244%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

2011PLoSO...614763M

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

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26 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21445244%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

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