(Q42708298)

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Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway

scientific article published on 19 November 2013

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Europe PubMed Central

PubMed publication ID

5 November 2017

Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

Mohamed A M El Gendy

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Hesham M Korashy

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Zaid H Maayah

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Mushtaq Ahmad Ansari

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Mohammed N Al-Arifi

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

19 November 2013

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Europe PubMed Central

PubMed publication ID

5 November 2017

Archives of Toxicology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

88

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

725-738

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24247421%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats

1 reference

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Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression.

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Chronic doxorubicin cardiotoxicity modulates cardiac cytochrome P450-mediated arachidonic acid metabolism in rats.

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Perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure sensitizes offspring to angiotensin II-induced hypertension

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Different structural requirements of the ligand binding domain of the aryl hydrocarbon receptor for high- and low-affinity ligand binding and receptor activation

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21 January 2018

Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells

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Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes

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PCBs alter gene expression of nuclear transcription factors and other heart-specific genes in cultures of primary cardiomyocytes: possible implications for cardiotoxicity

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Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: protection against oxidative and electrophilic injury

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EROD activity induction in peripheral blood lymphocytes, liver and brain tissues of rats orally exposed to polycyclic aromatic hydrocarbons

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21 January 2018

Hydrogen peroxide dose dependent induction of cell death or hypertrophy in cardiomyocytes.

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21 January 2018

Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib

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21 January 2018

Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1.

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21 January 2018

Cytochrome P450 enzymes: central players in cardiovascular health and disease

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21 January 2018

Differences in effects on myocardium and mitochondria by angiogenic inhibitors suggest separate mechanisms of cardiotoxicity

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21 January 2018

Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib

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Activation of the Ah receptor by tryptophan and tryptophan metabolites

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21 January 2018

Role of mitogen-activated protein kinases in aryl hydrocarbon receptor signaling

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21 January 2018

2,3,7,8-tetrachlorodibenzo-p-dioxin induces lecithin: retinol acyltransferase transcription in the rat kidney

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21 January 2018

Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension

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An investigation into creatine kinase and other plasma enzymes in thyroid disorders

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21 January 2018

Biochemical and molecular biological analysis of different responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin in chick embryo heart and liver

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21 January 2018

Sunitinib malate

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21 January 2018

Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase

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21 January 2018

Properties of a clonal muscle cell line from rat heart

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21 January 2018

Cardiosulfa induces heart deformation in zebrafish through the AhR-mediated, CYP1A-independent pathway.

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21 January 2018

Hypertension, cardiac hypertrophy, and impaired vascular relaxation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are associated with increased superoxide

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21 January 2018

Differential effects of mercury, lead and copper on the constitutive and inducible expression of aryl hydrocarbon receptor (AHR)-regulated genes in cultured hepatoma Hepa 1c1c7 cells.

1 reference

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21 January 2018

The role of aryl hydrocarbon receptor in the pathogenesis of cardiovascular diseases.

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21 January 2018

The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation

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21 January 2018

The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes

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21 January 2018

Cell signaling by receptor tyrosine kinases

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21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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21 January 2018

Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation

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21 January 2018

The androgenic anabolic steroid tetrahydrogestrinone produces dioxin-like effects via the aryl hydrocarbon receptor.

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21 January 2018

Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer

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21 January 2018

Ligand-dependent and -independent degradation of the human aryl hydrocarbon receptor (hAHR) in cell culture models

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CYP1A in TCDD toxicity and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates

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P-450 metabolites of arachidonic acid in the control of cardiovascular function

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21 January 2018

The aryl hydrocarbon receptor and its xenobiotic ligands: a fundamental trigger for cardiovascular diseases

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21 January 2018

Lipoxin A4: a new class of ligand for the Ah receptor

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21 January 2018

Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma

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Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid.

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Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1.

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Gene expression in distinct regions of the heart

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21 January 2018

Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types

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The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro

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Induction of several cytochrome P450 genes by doxorubicin in H9c2 cells.

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Role of NF-kappaB in the regulation of cytochrome P450 enzymes.

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2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism

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Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases

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Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats.

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21 January 2018

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