(Q34306783)

1 August 2017

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title

Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer (English)

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1 August 2017

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Daniel W Nebert

1

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1 August 2017

Timothy P Dalton

series ordinal

2

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1 August 2017

Allan B Okey

series ordinal

3

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1 August 2017

Frank J Gonzalez

series ordinal

4

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1 August 2017

language of work or name

English

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publication date

17 March 2004

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Journal of Biological Chemistry

1 August 2017

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1 August 2017

279

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1 August 2017

23847-23850

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1 August 2017

23

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Enzyme-catalysed reactions of polycyclic hydrocarbons with deoxyribonucleic acid and protein in vitro

1 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

The aryl hydrocarbon receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Aryl hydrocarbon receptors: diversity and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Polymorphisms in the human AH receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Metabolism of chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

High susceptibility to lung cancer analyzed in terms of combined genotypes of P450IA1 and Mu-class glutathione S-transferase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Polymorphisms of the CYP1A1 and GSTM1 genes in relation to individual susceptibility to lung carcinoma in Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Clinical importance of the cytochromes P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Role of gene knockout and transgenic mice in the study of xenobiotic metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Sequence variation and phylogenetic history of the mouse Ahr gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Aryl hydrocarbon receptor mediates benzene-induced hematotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Decrease in 4-aminobiphenyl-induced methemoglobinemia in Cyp1a2(-/-) knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Effect of CYP1A2 deficiency on heterocyclic amine DNA adduct levels in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

7,12-Dimethylbenz[a]anthracene-Induced Bone Marrow Toxicity Is p53-Dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Cytochrome P450 1B1 determines susceptibility to dibenzo[a,l]pyrene-induced tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

Tumour promotion by TCDD in skin of HRS/J hairless mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400004200

21 January 2018

Identifiers

DOI

10.1074/JBC.R400004200

1 reference

1 August 2017

1 reference