(Q42713015)

23392676

5 November 2017

title

Regulation of microglial proliferation during chronic neurodegeneration (English)

1 reference

Colony stimulating factor 1 receptor

5 November 2017

1 reference

1 reference

protein tyrosine kinase activity

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Colony stimulating factor 1 (macrophage)

1 reference

Colony stimulating factor 1 receptor

1 reference

Interleukin 34

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

Nina L. Fransen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

author name string

Stefano Suzzi

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

V Hugh Perry

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 February 2013

1 reference

23392676

5 November 2017

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

page(s)

2481-2493

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

describes a project that uses

15 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6619184/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Regeneration of a germinal layer in the adult mammalian brain

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PU.1 expression in microglia

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Expression of macrophage colony-stimulating factor receptor is increased in the AbetaPP(V717F) transgenic mouse model of Alzheimer's disease

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Atypical inflammation in the central nervous system in prion disease

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A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse.

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Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease

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Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses

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Functional analysis of PU.1 domains in monocyte-specific gene regulation

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12 December 2020

Microglial cell activation and proliferation precedes the onset of CNS autoimmunity

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Turnover of resident microglia in the normal adult mouse brain

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12 December 2020

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

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12 December 2020

TGFbeta1 regulates the inflammatory response during chronic neurodegeneration

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Early and rapid engraftment of bone marrow-derived microglia in scrapie.

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Systemic infections and inflammation affect chronic neurodegeneration

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CCAAT/enhancer binding protein-alpha is down-regulated by toll-like receptor agonists in microglial cells.

1 reference

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C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment

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Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

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Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

1 reference

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C/EBP alpha:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBP alpha homodimers or AP-1

1 reference

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Osteopetrotic (op/op) mice have reduced microglia, no Abeta deposition, and no changes in dopaminergic neurons

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Interleukin 15 expression in the CNS: blockade of its activity prevents glial activation after an inflammatory injury.

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Colony-stimulating factors in inflammation and autoimmunity.

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Upregulation of p21Cip1 in activated glial cells.

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Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

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Microglial physiology: unique stimuli, specialized responses

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Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

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An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

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Macrophage-colony stimulating factor as an inducer of microglial proliferation in axotomized rat facial nucleus.

1 reference

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Fate mapping analysis reveals that adult microglia derive from primitive macrophages

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Microglia in the CNS: immigrants from another world

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MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway.

1 reference

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Interleukin-15 regulates proliferation and self-renewal of adult neural stem cells

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Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

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Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis

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1 reference

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A lineage of myeloid cells independent of Myb and hematopoietic stem cells

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Ablation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutase

1 reference

12 December 2020

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

1 reference

12 December 2020

Impaired energy homeostasis in C/EBP alpha knockout mice

1 reference

12 December 2020

Inhibition of posttraumatic microglial proliferation in a genetic model of macrophage colony-stimulating factor deficiency in the mouse

1 reference

12 December 2020

Microglial and astroglial reactions to anterograde axonal degeneration: a histochemical and immunocytochemical study of the adult rat fascia dentata after entorhinal perforant path lesions

1 reference

12 December 2020

The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor

1 reference

12 December 2020

The transcription factor PU.1 is involved in macrophage proliferation

1 reference

12 December 2020

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

1 reference

12 December 2020

Regulation of MCSF receptors on microglia in the normal and injured mouse central nervous system: a quantitative immunofluorescence study using confocal laser microscopy

1 reference

12 December 2020

10.1523/JNEUROSCI.4440-12.2013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json

15 May 2020

23392676

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619184&resulttype=core&format=json