(Q42715507)

5 November 2017

title

GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia (English)

1 reference

5 November 2017

T Holmlund

1

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5 November 2017

M J Lindberg

series ordinal

2

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5 November 2017

D Grander

series ordinal

3

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5 November 2017

A E Wallberg

series ordinal

4

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5 November 2017

publication date

11 September 2012

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5 November 2017

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5 November 2017

volume

27

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5 November 2017

issue

3

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5 November 2017

page(s)

578-585

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The role of E2A-PBX1 in leukemogenesis

5 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Histone acetyltransferase complexes: one size doesn't fit all

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essential for a subset of transcriptional and oncogenic properties of E2a-Pbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Regulation of E2A activities by histone acetyltransferases in B lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Mapping acetylation sites in E2A identifies a conserved lysine residue in activation domain 1 that promotes CBP/p300 recruitment and transcriptional activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Critical role for a single leucine residue in leukemia induction by E2A-PBX1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Design, synthesis, and biological evaluation of a small-molecule inhibitor of the histone acetyltransferase Gcn5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Mechanisms of P/CAF auto-acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Regulation of the p300 HAT domain via a novel activation loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Romidepsin: a novel histone deacetylase inhibitor for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

Histone acetyltransferase inhibitors and preclinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

inferred from DOI database lookup

7 January 2021

based on heuristic

Flow cytometric follow-up of minimal residual disease in bone marrow gives prognostic information in children with acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

inferred from DOI database lookup

7 January 2021

based on heuristic

The histone acetyltransferase activity of human GCN5 and PCAF is stabilized by coenzymes

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.265

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2012.265

1 reference

Dimensions Publication ID

5 November 2017

1048073341

0 references

1 reference