(Q42721175)

5 November 2017

T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures (English)

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5 November 2017

11

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5 November 2017

18

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5 November 2017

Kim L Powell

2

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Terrance P Snutch

19

object named as

Terrance P Snutch

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5 November 2017

3

Stuart M Cain

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5 November 2017

12

Emma Braine

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5 November 2017

13

Gil Rind

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5 November 2017

Elizabeth Tringham

1

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5 November 2017

Kristy Kuplast

4

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5 November 2017

Janette Mezeyova

5

1 reference

5 November 2017

Manjula Weerapura

6

1 reference

5 November 2017

Cyrus Eduljee

7

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5 November 2017

Xinpo Jiang

8

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5 November 2017

Paula Smith

9

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5 November 2017

Jerrie-Lynn Morrison

10

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5 November 2017

Molly Fee-Maki

14

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5 November 2017

David Parker

15

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5 November 2017

Hassan Pajouhesh

16

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5 November 2017

Manjeet Parmar

17

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5 November 2017

language of work or name

English

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publication date

1 February 2012

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Science Translational Medicine

5 November 2017

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5 November 2017

4

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5 November 2017

121

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5 November 2017

121ra19

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Absence seizures: a review of recent reports with new concepts

5 November 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Modulators of voltage-dependent calcium channels for the treatment of nervous system diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Curing epilepsy: progress and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Role of voltage-gated calcium channels in epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Baseline cognition, behavior, and motor skills in children with new-onset, idiopathic epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Pathophysiological mechanisms of genetic absence epilepsy in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Corticothalamic 5-9 Hz oscillations are more pro-epileptogenic than sleep spindles in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Actions of U-92032, a T-type Ca2+ channel antagonist, support a functional linkage between I(T) and slow intrathalamic rhythms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Block of Thalamic T-Type Ca(2+) Channels by Ethosuximide Is Not the Whole Story.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Ethosuximide: from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Role of the alpha1G T-type calcium channel in spontaneous absence seizures in mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Association between genetic variation of CACNA1H and childhood absence epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

New variants in the CACNA1H gene identified in childhood absence epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Common polymorphisms in the CACNA1H gene associated with childhood absence epilepsy in Chinese Han population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Mutational analysis of CACNA1G in idiopathic generalized epilepsy. Mutation in brief #962. Online.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Gating effects of mutations in the Cav3.2 T-type calcium channel associated with childhood absence epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Effects of Cav3.2 channel mutations linked to idiopathic generalized epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Functional analysis of Ca3.2 T-type calcium channel mutations linked to childhood absence epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Functional characterization and neuronal modeling of the effects of childhood absence epilepsy variants of CACNA1H, a T-type calcium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

The I-II loop controls plasma membrane expression and gating of Ca(v)3.2 T-type Ca2+ channels: a paradigm for childhood absence epilepsy mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Targeting chronic and neuropathic pain: the N-type calcium channel comes of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Characterization of lamotrigine inhibition of Na+ channels in rat hippocampal neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Scaffold-based design and synthesis of potent N-type calcium channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Neuropeptide Y suppresses absence seizures in a genetic rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Low-voltage-activated calcium channel subunit expression in a genetic model of absence epilepsy in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Different kinetic properties of two T-type Ca2+ currents of rat reticular thalamic neurones and their modulation by enflurane

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca(v)3.3 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

CaV3.2 is the major molecular substrate for redox regulation of T-type Ca2+ channels in the rat and mouse thalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

The role of T-channels in the generation of thalamocortical rhythms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

The initiation of bursts in thalamic neurons and the cortical control of thalamic sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Calcium currents in rat thalamocortical relay neurones: kinetic properties of the transient, low-threshold current.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Ionic basis for the electro-responsiveness and oscillatory properties of guinea-pig thalamic neurones in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Electrophysiology of mammalian thalamic neurones in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Targeting thalamic nuclei is not sufficient for the full anti-absence action of ethosuximide in a rat model of absence epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Cellular interactions in the rat somatosensory thalamocortical system during normal and epileptic 5-9 Hz oscillations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Deep layer somatosensory cortical neurons initiate spike-and-wave discharges in a genetic model of absence seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Differential expression of T-type calcium channels in P/Q-type calcium channel mutant mice with ataxia and absence epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

The effects of ethosuximide on amino acids in genetic absence epilepsy rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Lack of delta waves and sleep disturbances during non-rapid eye movement sleep in mice lacking alpha1G-subunit of T-type calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

In vitro characterization of T-type calcium channel antagonist TTA-A2 and in vivo effects on arousal in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

The mechanism of carbamazepine aggravation of absence seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Elevated anxiety and depressive-like behavior in a rat model of genetic generalized epilepsy suggesting common causation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

Intrinsic oscillations of neocortex generated by layer 5 pyramidal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003120

10.1126/SCITRANSLMED.3003120

21 January 2018

Identifiers

DOI

1 reference

5 November 2017

1 reference