(Q42728392)

English

Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization.

scientific article published on 16 March 2011

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27 January 2020

Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization (English)

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27 January 2020

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27 January 2020

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27 January 2020

author name string

Kirk W Siddals

1

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27 January 2020

Justine Allen

2

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27 January 2020

Smeeta Sinha

3

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27 January 2020

Philip A Kalra

5

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27 January 2020

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16 March 2011

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27 January 2020

Journal of Biological Chemistry

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27 January 2020

286

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27 January 2020

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27 January 2020

16623-16630

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27 January 2020

Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression

1 reference

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27 May 2018

Efficacy of simvastatin treatment of valvular interstitial cells varies with the extracellular environment

1 reference

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27 May 2018

Vascular calcification: pathobiology of a multifaceted disease

1 reference

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27 May 2018

BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Modulation of calcification of vascular smooth muscle cells in culture by calcium antagonists, statins, and their combination

1 reference

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27 May 2018

Pharmacogenomics of human OATP transporters

1 reference

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27 May 2018

Progressive coronary calcification despite intensive lipid-lowering treatment: a randomised controlled trial

1 reference

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27 May 2018

HMG-CoA reductase inhibitors induce apoptosis in pericytes

1 reference

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27 May 2018

Bone morphogenetic proteins in vascular calcification

1 reference

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27 May 2018

Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial

1 reference

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27 May 2018

A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Angiogenesis and pericytes in the initiation of ectopic calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Vascular calcification mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Effect of recombinant porcine IGFBP-3 on IGF-I and long-R3-IGF-I-stimulated proliferation and differentiation of L6 myogenic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion: synergy between protein prenylation and receptor glycosylation pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Induction of osteoblast differentiation indices by statins in MC3T3-E1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Vascular calcification: mechanisms and clinical ramifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

The ins(ide) and out(side) of dolichyl phosphate biosynthesis and recycling in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

IGF-I receptor signalling in transformation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Non-lipid-related effects of statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Effect of alternative glycosylation on insulin receptor processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Expression of the insulin-like growth factor 1 receptor (IGF-1R) in breast cancer cells: evidence for a regulatory role of dolichyl phosphate in the transition from an intracellular to an extracellular IGF-1 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Regulatory role of mevalonate and N-linked glycosylation in proliferation and expression of the EWS/FLI-1 fusion protein in Ewing's sarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

The dolichol pathway of N-linked glycosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Regulation of proliferation and Ras localization in transformed cells by products of mevalonate metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Bone morphogenetic protein expression in human atherosclerotic lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Specific glycosylation site mutations of the insulin receptor alpha subunit impair intracellular transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Dissecting glycoprotein biosynthesis by the use of specific inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Dolichol delays G1-arrest for one cell cycle in human fibroblasts subjected to depletion of serum or mevalonate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

27 May 2018

Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 June 2018

Inhibition of the mevalonate pathway rescues the dexamethasone-induced suppression of the mineralization in osteoblasts via enhancing bone morphogenetic protein-2 signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

Effect of intensive versus standard lipid-lowering treatment with atorvastatin on the progression of calcified coronary atherosclerosis over 12 months: a multicenter, randomized, double-blind trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

Cartilaginous metaplasia in calcified diabetic peripheral vascular disease: Morphologic evidence of enchondral ossification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

Lovastatin stimulates human vascular smooth muscle cell expression of bone morphogenetic protein-2, a potent inhibitor of low-density lipoprotein-stimulated cell growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

Significance of calcification of the coronary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089505

16 August 2018

An alternative cis-isoprenyltransferase activity in yeast that produces polyisoprenols with chain lengths similar to mammalian dolichols

1 reference

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21 January 2018

Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.202929

21 January 2018

Isoprenoids and astroglial cell cycling: Diminished mevalonate availability and inhibition of dolichol-linked glycoprotein synthesis arrest cycling through distinct mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

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inferred from PubMed ID database lookup

Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical implications. A statement for health professionals from the American Heart Association. Writing Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human and porcine smooth muscle cells share similar proliferation dependence on the mevalonate pathway: implication for in vivo interventions in the porcine model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcification of human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct vascular effects of HMG-CoA reductase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcification in atherosclerotic plaque of human carotid arteries: associations with mast cells and macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on bone formation and remodelling in advanced atherosclerotic lesions of human carotid arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mineralocorticoid receptor activation promotes vascular cell calcification

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic effects of statins in atherosclerosis and diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.202929

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21454560%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21454560%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21454560%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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