(Q42738598)

6 November 2017

An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension (English)

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6 November 2017

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Clay F Semenkovich

9

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author name string

Carlos Bernal-Mizrachi

1

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6 November 2017

Liu Xiaozhong

2

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6 November 2017

Li Yin

3

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6 November 2017

Russell H Knutsen

4

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6 November 2017

Michael J Howard

5

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6 November 2017

Joop J A Arends

6

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6 November 2017

Pascual Desantis

7

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6 November 2017

Trey Coleman

8

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6 November 2017

1 February 2007

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6 November 2017

1 reference

6 November 2017

5

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6 November 2017

2

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6 November 2017

91-102

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PPARalpha activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans

6 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Effectiveness of vagus nerve stimulation in epilepsy patients: a 12-year observation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

PPARalpha governs glycerol metabolism

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

The mechanisms of action of PPARs

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

A transgenic model of visceral obesity and the metabolic syndrome

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Functional and chemical anatomy of the afferent vagal system

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Relative hypoglycemia and hyperinsulinemia in mice with heterozygous lipoprotein lipase (LPL) deficiency. Islet LPL regulates insulin secretion

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Selective vagal rhizotomies: a new dorsal surgical approach used for intestinal deafferentations.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Two-year outcome of vagus nerve stimulation (VNS) for treatment of major depressive episodes.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

The prandial insulin sensitivity-modifying effect of vagal stimulation in rats

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid accumulation and mitochondrial dysfunction

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Hypothalamic insulin signaling is required for inhibition of glucose production

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Involvement of the vagus nerves in the regulation of basal hepatic glucose production in conscious dogs

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Jejunal or portal vein infusions of lipids increase hepatic vagal afferent activity

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Important role of the hepatic vagus nerve in glucose uptake and production by the liver.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Interactions between oestradiol and glucocorticoid regulatory effects on liver-specific glucocorticoid-inducible genes: possible evidence for a role of hepatic 11beta-hydroxysteroid dehydrogenase type 1.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Direct and indirect effects of carbenoxolone on responses to glucocorticoids and noradrenaline in rat aorta.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

The afferent and preganglionic parasympathetic innervation of the rat liver, demonstrated by the retrograde transport of horseradish peroxidase.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Effects of total and selective abdominal vagotomies on water intake in rats.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899170

Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation

16 August 2018

1 reference

12 December 2020

Determination of phosphoenolpyruvate carboxykinase activity with deoxyguanosine 5′-diphosphate as nucleotide substrate

1 reference

12 December 2020

Comparison of the Effects of ‘Glucocorticoid’ And ‘Mineralocortocoid’ Infusions on Blood Pressure in Sheep

1 reference

12 December 2020

The effects of liver denervation on food and water intake in the rat

1 reference

12 December 2020

An anterograde tracing study of the vagal innervation of rat liver, portal vein and biliary system

1 reference

12 December 2020

Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids

1 reference

12 December 2020

Hepatic denervation does not significantly change the response of the liver to glucagon in conscious dogs

1 reference

12 December 2020

Expression of the Peroxisome Proliferator-activated Receptor Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

1 reference

12 December 2020

Insulin resistance caused by hepatic cholinergic interruption and reversed by acetylcholine administration

1 reference

12 December 2020

Mechanisms in the pressor effects of hepatic portal venous fatty acid infusion

1 reference

12 December 2020

Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity

1 reference

12 December 2020

10.1016/J.CMET.2006.12.010

Identifiers

DOI

1 reference

6 November 2017

1 reference

6 November 2017

PubMed publication ID

17276352

1 reference