(Q42746597)

6 November 2017

title

Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-ĸB. (English)

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6 November 2017

Hidehisa Shimizu

1

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6 November 2017

Dilinaer Bolati

2

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6 November 2017

Ayinuer Adijiang

3

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6 November 2017

Yelixiati Adelibieke

4

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6 November 2017

Gulinuer Muteliefu

5

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6 November 2017

Atsushi Enomoto

6

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6 November 2017

Yukihiro Higashiyama

7

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6 November 2017

Yusuke Higuchi

8

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6 November 2017

Fuyuhiko Nishijima

9

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6 November 2017

Toshimitsu Niwa

10

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6 November 2017

language of work or name

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9 March 2011

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American Journal of Nephrology

6 November 2017

published in

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6 November 2017

volume

33

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6 November 2017

issue

4

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6 November 2017

page(s)

319-324

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

6 November 2017

cites work

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21 January 2018

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Current understanding of klotho

21 January 2018

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Severely reduced production of klotho in human chronic renal failure kidney

21 January 2018

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Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity

21 January 2018

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Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells

21 January 2018

1 reference

Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate.

21 January 2018

1 reference

Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?

21 January 2018

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Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.

21 January 2018

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Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress.

21 January 2018

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ROS and PDGF-beta [corrected] receptors are critically involved in indoxyl sulfate actions that promote vascular smooth muscle cell proliferation and migration

21 January 2018

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Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells.

21 January 2018

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Indoxyl sulfate and atherosclerotic risk factors in hemodialysis patients.

21 January 2018

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Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats

21 January 2018

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NF-κB p65 represses β-catenin-activated transcription of cyclin D1.

21 January 2018

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Klotho is a target gene of PPAR-gamma.

21 January 2018

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Troglitazone Antagonizes Tumor Necrosis Factor-α-induced Reprogramming of Adipocyte Gene Expression by Inhibiting the Transcriptional Regulatory Functions of NF-κB

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000324885

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6 November 2017

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