(Q42750295)

6 November 2017

title

A possible mechanism for hepatotoxicity induced by BIRB-796, an orally active p38 mitogen-activated protein kinase inhibitor (English)

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6 November 2017

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Shunsuke Iwano

1

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6 November 2017

Yoshiji Asaoka

2

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6 November 2017

Hideo Akiyama

3

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6 November 2017

Satoko Takizawa

4

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6 November 2017

Hitoshi Nobumasa

5

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6 November 2017

Hisashi Hashimoto

6

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6 November 2017

Yohei Miyamoto

7

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6 November 2017

language of work or name

English

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publication date

16 February 2011

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Journal of Applied Toxicology

6 November 2017

published in

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6 November 2017

volume

31

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issue

7

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6 November 2017

page(s)

671-677

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Novel biologic therapies for psoriasis

6 November 2017

cites work

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Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia

21 January 2018

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Naphthalene-induced respiratory tract toxicity: metabolic mechanisms of toxicity.

21 January 2018

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Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases

21 January 2018

1 reference

Drug-protein adducts: an industry perspective on minimizing the potential for drug bioactivation in drug discovery and development

21 January 2018

1 reference

Role of cytokines in rheumatoid arthritis

21 January 2018

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Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice

21 January 2018

1 reference

Rat toxicogenomic study reveals analytical consistency across microarray platforms

21 January 2018

1 reference

Bromobenzene-induced hepatotoxicity at the transcriptome level

21 January 2018

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Biological agents for rheumatoid arthritis: targeting both physical function and structural damage

21 January 2018

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

21 January 2018

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Pathway and gene-set activation measurement from mRNA expression data: the tissue distribution of human pathways

21 January 2018

1 reference

Ultrasensitive DNA chip: gene expression profile analysis without RNA amplification.

21 January 2018

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The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

21 January 2018

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The current state of serum biomarkers of hepatotoxicity.

21 January 2018

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Covalent binding of xenobiotics to specific proteins in the liver

21 January 2018

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Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate

21 January 2018

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Structure−Activity Relationships of the p38α MAP Kinase Inhibitor 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796)

21 January 2018

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In vivo effects of ozone exposure on protein adduct formation by 1-nitronaphthalene in rat lung

21 January 2018

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Drug bioactivation, covalent binding to target proteins and toxicity relevance

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JAT.1622

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6 November 2017

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