(Q42776369)

8 June 2018

title

Epigenomics of human CD8 T cell differentiation and aging (English)

1 reference

8 June 2018

0 references

1 reference

Sabine Le Saux

4

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Bin Hu

Bin Hu

3

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David Moskowitz

David M Moskowitz

1

0 references

William Greenleaf

9

William J Greenleaf

1 reference

8 June 2018

7

Jason D Buenrostro

1 reference

8 June 2018

Cornelia Weyand

8

Cornelia M Weyand

1 reference

8 June 2018

author name string

David W Zhang

2

1 reference

8 June 2018

Rolando E Yanes

5

1 reference

8 June 2018

Zhongde Ye

6

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8 June 2018

Jörg J Goronzy

10

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8 June 2018

publication date

17 February 2017

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8 June 2018

published in

Science Immunology

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8 June 2018

volume

2

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8 June 2018

issue

8

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8 June 2018

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility

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Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

10 June 2018

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10 June 2018

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Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

10 June 2018

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Individuality and variation of personal regulomes in primary human T cells

10 June 2018

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Naive T cell maintenance and function in human aging

10 June 2018

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Long-lasting stem cell-like memory CD8+ T cells with a naïve-like profile upon yellow fever vaccination

10 June 2018

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Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover

10 June 2018

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Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation

10 June 2018

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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

10 June 2018

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10 June 2018

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Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories

10 June 2018

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Diversity and clonal selection in the human T-cell repertoire

10 June 2018

1 reference

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The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells

10 June 2018

1 reference

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Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans

10 June 2018

1 reference

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Ets-1 global gene expression profile reveals associations with metabolism and oxidative stress in ovarian and breast cancers

10 June 2018

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Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

10 June 2018

1 reference

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Global DNA methylation remodeling accompanies CD8 T cell effector function.

10 June 2018

1 reference

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Bach2 maintains T cells in a naive state by suppressing effector memory-related genes

10 June 2018

1 reference

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10 June 2018

The hallmarks of aging

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Understanding immunosenescence to improve responses to vaccines

10 June 2018

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Differential localization of T-bet and Eomes in CD8 T cell memory populations.

10 June 2018

1 reference

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Transcriptional control of effector and memory CD8+ T cell differentiation

10 June 2018

1 reference

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Immune senescence and vaccines to prevent herpes zoster in older persons

10 June 2018

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Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis

10 June 2018

1 reference

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A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

ChromHMM: automating chromatin-state discovery and characterization

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Derivation and maintenance of virtual memory CD8 T cells

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Removing technical variability in RNA-seq data using conditional quantile normalization

10 June 2018

1 reference

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Histone methylation makes its mark on longevity

10 June 2018

1 reference

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Pioneer transcription factors: establishing competence for gene expression

10 June 2018

1 reference

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Changes in gene expression induced by Sp1 knockdown differ from those caused by challenging Sp1 binding to gene promoters

10 June 2018

1 reference

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Pluripotency factors regulate definitive endoderm specification through eomesodermin

10 June 2018

1 reference

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Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

10 June 2018

1 reference

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GREAT improves functional interpretation of cis-regulatory regions

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Model-based analysis of ChIP-Seq (MACS)

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Clustering of DNA sequences in human promoters

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Mortality associated with influenza and respiratory syncytial virus in the United States

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Defective activation and survival of T cells lacking the Ets-1 transcription factor

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Competition between DNA methylation and transcription factors determines binding of NRF1.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399889

ETS-dependent regulation of a distal Gata4 cardiac enhancer

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIIMMUNOL.AAG0192

10.1126/SCIIMMUNOL.AAG0192

21 January 2018

Identifiers

DOI

1 reference

8 June 2018

PMC publication ID

5399889

1 reference

8 June 2018

PubMed publication ID

28439570

1 reference

8 June 2018