(Q42791258)

7 November 2017

Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis (English)

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7 November 2017

Julie A Di Paolo

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7 November 2017

Tao Huang

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7 November 2017

Mercedesz Balazs

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7 November 2017

James Barbosa

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7 November 2017

Kai H Barck

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7 November 2017

Brandon J Bravo

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7 November 2017

Richard A D Carano

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7 November 2017

James Darrow

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7 November 2017

Douglas R Davies

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7 November 2017

Laura E DeForge

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7 November 2017

Lauri Diehl

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7 November 2017

Ronald Ferrando

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7 November 2017

Steven L Gallion

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7 November 2017

Anthony M Giannetti

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7 November 2017

Peter Gribling

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7 November 2017

Vincent Hurez

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7 November 2017

Sarah G Hymowitz

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7 November 2017

Randall Jones

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7 November 2017

Jeffrey E Kropf

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7 November 2017

Wyne P Lee

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7 November 2017

Patricia M Maciejewski

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7 November 2017

Scott A Mitchell

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7 November 2017

Hong Rong

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7 November 2017

Bart L Staker

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7 November 2017

J Andrew Whitney

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7 November 2017

Sherry Yeh

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7 November 2017

Wendy B Young

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7 November 2017

Christine Yu

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7 November 2017

Juan Zhang

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7 November 2017

Karin Reif

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7 November 2017

Kevin S Currie

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7 November 2017

28 November 2010

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7 November 2017

Nature Chemical Biology

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7 November 2017

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7 November 2017

41-50

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https://scigraph.springernature.com/pub.10.1038/nchembio.481

7 November 2017

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cites work

Bruton's Tyrosine Kinase is involved in innate and adaptive immunity

1 reference

12 December 2020

B cell-directed therapy in rheumatoid arthritis--clinical experience.

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12 December 2020

The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases

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12 December 2020

Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

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12 December 2020

Autoantibodies to citrullinated proteins: ACPA.

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12 December 2020

The role of antibodies in mouse models of rheumatoid arthritis, and relevance to human disease

1 reference

12 December 2020

Chemical genetics: where genetics and pharmacology meet

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12 December 2020

The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation

1 reference

12 December 2020

FcgammaRIII-expressing macrophages are essential for development of collagen-induced arthritis

1 reference

12 December 2020

The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective

1 reference

12 December 2020

Regulation of B-cell activation and differentiation by the phosphatidylinositol 3-kinase and phospholipase Cgamma pathway

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12 December 2020

The importance of IL-1 beta and TNF-alpha, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis

1 reference

12 December 2020

The role of Tec family kinases in myeloid cells

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12 December 2020

Contribution of Fcgamma receptor IIIA gene 158V/F polymorphism and copy number variation to the risk of ACPA-positive rheumatoid arthritis.

1 reference

12 December 2020

Bruton's tyrosine kinase as a drug discovery target

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12 December 2020

A quantitative analysis of kinase inhibitor selectivity

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12 December 2020

A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis

1 reference

12 December 2020

Collagen-induced arthritis in the BB rat. Prevention of disease by treatment with CTLA-4-Ig

1 reference

12 December 2020

Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling

1 reference

12 December 2020

Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker

1 reference

12 December 2020

A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

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12 December 2020

Roles of Fc receptors in autoimmunity

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12 December 2020

Antibodies to type II collagen in early rheumatoid arthritis. Correlation with disease progression

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12 December 2020

Genes on the X chromosome affect development of collagen-induced arthritis in mice

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12 December 2020

Induction of macrophage secretion of tumor necrosis factor alpha through Fcgamma receptor IIa engagement by rheumatoid arthritis-specific autoantibodies to citrullinated proteins complexed with fibrinogen

1 reference

12 December 2020

Btk regulates B cell receptor-mediated antigen processing and presentation by controlling actin cytoskeleton dynamics in B cells

1 reference

12 December 2020

Essential role of Fc gamma receptors in anti-type II collagen antibody-induced arthritis

1 reference

12 December 2020

Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

1 reference

12 December 2020

Dual functions of Bruton's tyrosine kinase and Tec kinase during Fcgamma receptor-induced signaling and phagocytosis.

1 reference

12 December 2020

Pleiotropic consequences of Bruton tyrosine kinase deficiency in myeloid lineages lead to poor inflammatory responses

1 reference

12 December 2020

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

1 reference

12 December 2020

Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.

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12 December 2020

Rational design of inhibitors that bind to inactive kinase conformations

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12 December 2020

B-lymphocyte contributions to human autoimmune disease

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12 December 2020

A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis

1 reference

12 December 2020

Activation loop phosphorylation modulates Bruton's tyrosine kinase (Btk) kinase domain activity

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12 December 2020

B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity

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12 December 2020

Role of Bruton's tyrosine kinase in immunodeficiency

1 reference

12 December 2020

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases

1 reference

12 December 2020

Induction of costimulatory molecules B7-1 and B7-2 in murine B cells. the CBA/N mouse reveals a role for Bruton's tyrosine kinase in CD40-mediated B7 induction

1 reference

12 December 2020

Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production

1 reference

12 December 2020

Autoantibody profiling as early diagnostic and prognostic tool for rheumatoid arthritis

1 reference

12 December 2020

Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity.

1 reference

12 December 2020

Surface-bound anti-type II collagen-containing immune complexes induce production of tumor necrosis factor alpha, interleukin-1beta, and interleukin-8 from peripheral blood monocytes via Fc gamma receptor IIA: a potential pathophysiologic mechanism

1 reference

12 December 2020

Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice

1 reference

12 December 2020

Regulation of B lymphocyte development and activation by Bruton's tyrosine kinase

1 reference

12 December 2020

The complex role of Fcgamma receptors in the pathology of arthritis

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12 December 2020

Fcgamma receptors as regulators of immune responses

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12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.481

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Dimensions Publication ID

7 November 2017

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