(Q42802558)

English

Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction.

scientific article published on 4 December 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22138576%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22138576%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

3

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17 January 2020

Michael R. Speicher

13

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17 January 2020

Karl Lenhard Rudolph

14

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17 January 2020

2

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17 January 2020

Kodandaramireddy Nalapareddy

4

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17 January 2020

Luis Miguel Guachalla

5

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17 January 2020

11

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17 January 2020

Martin Burkhalter

8

object named as

Martin D Burkhalter

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17 January 2020

1

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Tobias Sperka

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17 January 2020

6

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André Lechel

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17 January 2020

author name string

Monika Mach

9

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17 January 2020

Falk Schlaudraff

10

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17 January 2020

Zhenyu Ju

12

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17 January 2020

Yvonne Begus-Nahrmann

7

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17 January 2020

publication date

4 December 2011

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17 January 2020

Nature Cell Biology

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17 January 2020

14

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17 January 2020

1

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17 January 2020

73-79

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17 January 2020

https://scigraph.springernature.com/pub.10.1038/ncb2388

0 references

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1 reference

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21 January 2018

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

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Aging and genome maintenance: lessons from the mouse?

1 reference

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

1 reference

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Apoptosis pathways in fungal growth, development and ageing.

1 reference

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21 January 2018

Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency

1 reference

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21 January 2018

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Puma is required for p53-induced depletion of adult stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

1 reference

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21 January 2018

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

1 reference

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21 January 2018

Block in anaphase chromosome separation caused by a telomerase template mutation.

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Identification of stem cells in small intestine and colon by marker gene Lgr5

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Identification of a putative intestinal stem cell and early lineage marker; musashi-1.

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

1 reference

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21 January 2018

Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis.

1 reference

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21 January 2018

Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Telomerase mutations in families with idiopathic pulmonary fibrosis

1 reference

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21 January 2018

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

1 reference

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21 January 2018

Single-cell isolation from cell suspensions and whole genome amplification from single cells to provide templates for CGH analysis

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21 January 2018

A multiplex PCR predictor for aCGH success of FFPE samples

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21 January 2018

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice

1 reference

https://api.crossref.org/works/10.1038%2FNCB2388

21 January 2018

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

1 reference

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21 January 2018

Small bowel enterocyte apoptosis and proliferation are increased in the elderly

1 reference

https://pubmed.ncbi.nlm.nih.gov/22138576

12 December 2020

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Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22138576

12 December 2020

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Telomere shortening associated with disease evolution patterns in myelodysplastic syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22138576

12 December 2020

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Increased apoptosis of T cell subsets in aging humans: altered expression of Fas (CD95), Fas ligand, Bcl-2, and Bax.

1 reference

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12 December 2020

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Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22138576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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