(Q42803499)

7 November 2017

title

Reversible membrane interaction of BAD requires two C-terminal lipid binding domains in conjunction with 14-3-3 protein binding (English)

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7 November 2017

Mirko Hekman

1

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7 November 2017

Stefan Albert

2

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7 November 2017

Antoine Galmiche

3

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7 November 2017

Ulrike E E Rennefahrt

4

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7 November 2017

Jochen Fueller

5

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7 November 2017

Andreas Fischer

6

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7 November 2017

Dirk Puehringer

7

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7 November 2017

Stefan Wiese

8

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7 November 2017

Ulf R Rapp

9

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7 November 2017

language of work or name

English

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publication date

7 April 2006

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

281

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7 November 2017

issue

25

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7 November 2017

page(s)

17321-17336

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BCL-2 family members and the mitochondria in apoptosis

7 November 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

21 January 2018

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

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Apoptotic pathways: ten minutes to dead

21 January 2018

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Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers

21 January 2018

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600292200

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

Bcl-2 proteins: master switches at the intersection of death signaling and the survival control by Raf kinases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association

21 January 2018

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Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis

21 January 2018

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Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells

21 January 2018

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The structure of the C-terminal domain of the pro-apoptotic protein Bak and its interaction with model membranes.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

Conformation of the C-terminal domain of the pro-apoptotic protein Bax and mutants and its interaction with membranes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

Associations of B- and C-Raf with cholesterol, phosphatidylserine, and lipid second messengers: preferential binding of Raf to artificial lipid rafts.

21 January 2018

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Bacterial cytotoxins: targeting eukaryotic switches

21 January 2018

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Diverse effects of RacV12 on cell transformation by Raf: partial inhibition of morphological transformation versus deregulation of cell cycle control

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600292200

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

21 January 2018

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Lipid rafts and signal transduction

21 January 2018

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The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade

21 January 2018

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Segregation of Bad from lipid rafts is implicated in the induction of apoptosis.

21 January 2018

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Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation

21 January 2018

1 reference

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Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600292200

Pharmacological manipulation of cell death: clinical applications in sight?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600292200

Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis

21 January 2018

1 reference

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Rafts: a simple way to control apoptosis by subcellular redistribution

21 January 2018

1 reference

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Phospholipid asymmetry of the outer membrane of rat liver mitochondria

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M600292200

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7 November 2017

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