(Q42804452)

English

Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells

scientific article published on 10 March 2006

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scholarly article

1 reference

Europe PubMed Central

7 November 2017

Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells (English)

1 reference

Europe PubMed Central

7 November 2017

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1 reference

based on heuristic

inferred from title

Nils Billestrup

5

1 reference

Europe PubMed Central

7 November 2017

object named as

S Papa

3

0 references

Thomas Mandrup-Poulsen

object named as

T Mandrup-Poulsen

6

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author name string

C M Larsen

1

1 reference

Europe PubMed Central

7 November 2017

M G Døssing

2

1 reference

Europe PubMed Central

7 November 2017

G Franzoso

4

1 reference

Europe PubMed Central

7 November 2017

language of work or name

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based on heuristic

inferred from title

publication date

10 March 2006

1 reference

Europe PubMed Central

7 November 2017

1 reference

Europe PubMed Central

7 November 2017

49

1 reference

Europe PubMed Central

7 November 2017

5

1 reference

Europe PubMed Central

7 November 2017

980-989

1 reference

Europe PubMed Central

7 November 2017

https://scigraph.springernature.com/pub.10.1007/s00125-006-0164-0

0 references

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

1 reference

https://api.crossref.org/works/10.1007%2FS00125-006-0164-0

21 January 2018

Reversibility of interleukin-1 beta-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1007%2FS00125-006-0164-0

21 January 2018

Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell survival and a Gadd45-factor deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myeloid differentiation (MyD) primary response genes in hematopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary response genes induced by growth factors and tumor promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the gadd45beta promoter by NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of human islets from the effects of interleukin-1beta by adenoviral gene transfer of an Ikappa B repressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor potentiates the beta-cell inhibitory effect of IL-1beta in rat pancreatic islets associated with increased nitric oxide synthesis and increased expression of inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IB1 reduces cytokine-induced apoptosis of insulin-secreting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gadd45beta is important for perpetuating cognate and inflammatory signals in T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of the c-Jun N-terminal kinase pathway by 17beta-estradiol can preserve human islet functional mass from proinflammatory cytokine-induced destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective po

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathogenesis of insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16528573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-006-0164-0

1 reference

Europe PubMed Central

7 November 2017

1 reference

Europe PubMed Central

7 November 2017

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