(Q42807654)

7 November 2017

title

Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation (English)

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7 November 2017

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McGuire TF

1

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7 November 2017

Qian Y

2

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7 November 2017

Vogt A

3

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7 November 2017

Hamilton AD

4

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7 November 2017

Sebti SM

5

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7 November 2017

language of work or name

English

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publication date

1 November 1996

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Journal of Biological Chemistry

7 November 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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7 November 2017

volume

271

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7 November 2017

issue

44

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7 November 2017

page(s)

27402-27407

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Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

7 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

The p21 ras C-terminus is required for transformation and membrane association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

21 January 2018

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Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

21 January 2018

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Phosphinyl acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.

21 January 2018

1 reference

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Disruption of Oncogenic K-Ras4B Processing and Signaling by a Potent Geranylgeranyltransferase I Inhibitor

21 January 2018

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Signal transduction. How receptors turn Ras on.

21 January 2018

1 reference

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Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

21 January 2018

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Oncogenes and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

CAAX peptidomimetic FTI-244 decreases platelet-derived growth factor receptor tyrosine phosphorylation levels and inhibits stimulation of phosphatidylinositol 3-kinase but not mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Lovastatin Disrupts Early Events in Insulin Signaling: A Potential Mechanism of Lovastatins Anti-Mitogenic Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

p21ras is modified by a farnesyl isoprenoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

CAAX geranylgeranyl transferase transfers farnesyl as efficiently as geranylgeranyl to RhoB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

A small GTP-binding protein, Rho, associates with the platelet-derived growth factor type-beta receptor upon ligand binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.44.27402

21 January 2018

Identifiers

DOI

10.1074/JBC.271.44.27402

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7 November 2017

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