(Q54177555)

25 May 2018

title

Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro. (English)

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25 May 2018

2

J L Goldstein

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25 May 2018

author name string

G L James

series ordinal

1

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25 May 2018

M S Brown

series ordinal

3

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25 May 2018

language of work or name

English

0 references

publication date

1 March 1995

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25 May 2018

Journal of Biological Chemistry

number of pages

6

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based on heuristic

inferred from page(s)

published in

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25 May 2018

volume

270

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25 May 2018

issue

11

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25 May 2018

page(s)

6221-6226

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25 May 2018

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

1 reference

Extracellular signals and reversible protein phosphorylation: what to Mek of it all.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

All ras proteins are polyisoprenylated but only some are palmitoylated

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Protein prenylation: genes, enzymes, targets, and functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Isoprenoid diphosphate utilization by recombinant human farnesyl:protein transferase: interactive binding between substrates and a preferred kinetic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Inhibitors of Ras farnesyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

p21ras is modified by a farnesyl isoprenoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Cloning and expression of a cDNA encoding the alpha subunit of rat p21ras protein farnesyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Steady-state kinetic mechanism of Ras farnesyl:protein transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Retinal degeneration in choroideremia: deficiency of rab geranylgeranyl transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

The pathway to signal achievement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.11.6221

21 January 2018

Identifiers

DOI

10.1074/JBC.270.11.6221

1 reference

25 May 2018

1 reference

25 May 2018