(Q42807684)

English

Resistance to the cytotoxic effects of tumor necrosis factor alpha can be overcome by inhibition of a FADD/caspase-dependent signaling pathway

scientific article published on December 1999

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scholarly article

1 reference

Europe PubMed Central

7 November 2017

Resistance to the cytotoxic effects of tumor necrosis factor alpha can be overcome by inhibition of a FADD/caspase-dependent signaling pathway (English)

1 reference

Europe PubMed Central

7 November 2017

0 references

author name string

Khwaja A

1

1 reference

Europe PubMed Central

7 November 2017

Tatton L

2

1 reference

Europe PubMed Central

7 November 2017

language of work or name

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publication date

1 December 1999

1 reference

Europe PubMed Central

7 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

7 November 2017

274

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Europe PubMed Central

7 November 2017

36817-36823

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Europe PubMed Central

7 November 2017

51

1 reference

Europe PubMed Central

7 November 2017

The biology of cachectin/TNF--a primary mediator of the host response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Cell death induction by receptors of the TNF family: towards a molecular understanding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Cell death induction by TNF: a matter of self control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Stimulus-dependent synergism of the antiapoptotic tumor necrosis factor receptor-associated factor 2 (TRAF2) and nuclear factor kappaB pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Mitochondrial permeability transition is a central coordinating event of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

The mitochondrial death/life regulator in apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Inhibition of mitochondrial respiratory chain complex I by TNF results in cytochrome c release, membrane permeability transition, and apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Inhibition of TNF-induced apoptosis by NF-kappa B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

FLICE Induced Apoptosis in a Cell-free System

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

TNF-alpha activates at least two apoptotic signaling cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Disulfiram is a potent inhibitor of proteases of the caspase family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.51.36817

21 January 2018

Identifiers

10.1074/JBC.274.51.36817

1 reference

Europe PubMed Central

7 November 2017

1 reference

Europe PubMed Central

7 November 2017

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