(Q42811646)

English

Binding of calmodulin to the carboxy-terminal region of p21 induces nuclear accumulation via inhibition of protein kinase C-mediated phosphorylation of Ser153.

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4 January 2020

Binding of calmodulin to the carboxy-terminal region of p21 induces nuclear accumulation via inhibition of protein kinase C-mediated phosphorylation of Ser153 (English)

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4 January 2020

phosphorylation

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9

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4 January 2020

4

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4 January 2020

author name string

Aina Rodríguez-Vilarrupla

1

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4 January 2020

Montserrat Jaumot

2

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4 January 2020

Neus Abella

3

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4 January 2020

Sonia Brun

5

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4 January 2020

Carmen Díaz

6

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4 January 2020

Josep M Estanyol

7

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4 January 2020

Oriol Bachs

8

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4 January 2020

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1 August 2005

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4 January 2020

Molecular and Cellular Biology

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4 January 2020

25

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4 January 2020

16

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4 January 2020

7364-7374

1 reference

Europe PubMed Central

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4 January 2020

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

1 reference

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Regulation of the cytoskeleton: an oncogenic function for CDK inhibitors?

1 reference

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27 May 2018

Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients.

1 reference

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27 May 2018

Cytoplasmic p21Cip1 Is Involved in Ras-induced Inhibition of the ROCK/LIMK/Cofilin Pathway

1 reference

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27 May 2018

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

1 reference

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27 May 2018

Are p27 and p21 cytoplasmic oncoproteins?

1 reference

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27 May 2018

PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein.

1 reference

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27 May 2018

The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

1 reference

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27 May 2018

Identification of the nuclear localization signal of p21(cip1) and consequences of its mutation on cell proliferation.

1 reference

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27 May 2018

Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity

1 reference

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27 May 2018

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival

1 reference

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27 May 2018

p21(Cip1) Promotes cyclin D1 nuclear accumulation via direct inhibition of nuclear export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer. association with prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

p21(WAF1/Cip1): more than a break to the cell cycle?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Calmodulin: a prototypical calcium sensor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Identification of CIP-1-associated regulator of cyclin B (CARB), a novel p21-binding protein acting in the G2 phase of the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Reversible phosphorylation at the C-terminal regulatory domain of p21(Waf1/Cip1) modulates proliferating cell nuclear antigen binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Regulatory cascades involving calmodulin-dependent protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Calmodulin binds to p21(Cip1) and is involved in the regulation of its nuclear localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

The Ca-calmodulin-dependent protein kinase cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Mitochondrial regulation of cell death: mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Ca2+-calmodulin and protein kinase Cs: a hypothetical synthesis of their conflicting convergences on shared substrate domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Calmodulin is essential for cyclin-dependent kinase 4 (Cdk4) activity and nuclear accumulation of cyclin D1-Cdk4 during G1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

New nuclear functions for calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

New functional activities for the p21 family of CDK inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Calcium binding and conformational response in EF-hand proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

A non-enzymatic p21 protein inhibitor of stress-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Regulation of the cell cycle by calcium and calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Ca(2+)-binding and structural dynamics in the functions of calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/CIP1/WAF1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Calmodulin--an intracellular calcium receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Calmodulin Plays a Pivotal Role in Cellular Regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

27 May 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

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27 May 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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27 May 2018

Distinct PKC isoforms mediate cell survival and DNA synthesis in thrombin-induced myofibroblasts.

1 reference

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16 August 2018

Regulation of nuclear import by phosphorylation adjacent to nuclear localization signals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

16 August 2018

The structural plasticity of the C terminus of p21Cip1 is a determinant for target protein recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190259

16 August 2018

Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia.

1 reference

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16 August 2018

PKCeta associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes.

1 reference

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16 August 2018

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

1 reference

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16 August 2018

Solution structure of p21(Waf1/Cip1/Sdi1) C-terminal domain bound to Cdk4

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Protein SET Regulates the Inhibitory Effect of p21Cip1on Cyclin E-Cyclin-dependent Kinase 2 Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.25.16.7364-7374.2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16055744%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16055744%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16055744%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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