(Q71985306)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

title

Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1 (English)

1 reference

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22 October 2019

5

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22 October 2019

author name string

K L Ball

1

1 reference

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22 October 2019

S Lain

2

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22 October 2019

R Fâhraeus

3

1 reference

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22 October 2019

C Smythe

4

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22 October 2019

language of work or name

English

0 references

publication date

1 January 1997

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22 October 2019

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22 October 2019

volume

7

1 reference

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22 October 2019

page(s)

71-80

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22 October 2019

issue

1

1 reference

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p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

22 October 2019

cites work

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

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7 January 2021

Sequence-specific transcriptional activation is essential for growth suppression by p53.

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

p53 mutations in human cancers

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Cancer. p53, guardian of the genome

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

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7 January 2021

Activation of the cryptic DNA binding function of mutant forms of p53.

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7 January 2021

Small peptides activate the latent sequence-specific DNA binding function of p53.

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7 January 2021

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

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7 January 2021

Inhibition of cyclin-dependent kinases by p21

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7 January 2021

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

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7 January 2021

The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition

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7 January 2021

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

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7 January 2021

G1 phase progression: cycling on cue

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7 January 2021

Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A

1 reference

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7 January 2021

Cyclin-binding motifs are essential for the function of p21CIP1

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7 January 2021

Analysis of wild-type and mutant p21WAF-1 gene activities

1 reference

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7 January 2021

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

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7 January 2021

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

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7 January 2021

Human and plant proliferating-cell nuclear antigen have a highly conserved binding site for the p53-inducible gene product p21WAF1

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7 January 2021

Minimization of a polypeptide hormone

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7 January 2021

Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptide

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7 January 2021

p53 mutations in human immortalized epithelial cell lines

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7 January 2021

Signalling targets for anticancer drug development

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7 January 2021

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

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7 January 2021

The 3Rs of life: Ras, Raf and growth regulation

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7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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7 January 2021

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7 January 2021

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7 January 2021

Antibody-antigen complexes

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7 January 2021

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

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7 January 2021

Thermodynamic analysis of an antibody functional epitope

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7 January 2021

A hot spot of binding energy in a hormone-receptor interface

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7 January 2021

Cloning and characterization of the Xenopus cyclin-dependent kinase inhibitor p27XIC1.

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7 January 2021

p21-containing cyclin kinases exist in both active and inactive states

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7 January 2021

10.1016/S0960-9822(06)00029-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

1 reference