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Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1
scientific article published on 01 January 1997
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Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
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22 October 2019
title
Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
author
David P. Lane
series ordinal
5
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Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
author name string
K L Ball
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
8999999
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
S Lain
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
R Fâhraeus
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
C Smythe
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
language of work or name
English
0 references
publication date
1 January 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
published in
Current Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
volume
7
1 reference
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Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
page(s)
71-80
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
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22 October 2019
cites work
p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte apoptosis induced by p53-dependent and independent pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 is required for radiation-induced apoptosis in mouse thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence-specific transcriptional activation is essential for growth suppression by p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WAF1, a potential mediator of p53 tumor suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21 is a universal inhibitor of cyclin kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of the growth inhibitor IGF-binding protein 3 by p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 mutations in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer. p53, guardian of the genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the cryptic DNA binding function of mutant forms of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small peptides activate the latent sequence-specific DNA binding function of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of cyclin-dependent kinases by p21
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 is a nuclear protein required for cell cycle progression in G1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G1 phase progression: cycling on cue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin-binding motifs are essential for the function of p21CIP1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of wild-type and mutant p21WAF-1 gene activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human and plant proliferating-cell nuclear antigen have a highly conserved binding site for the p53-inducible gene product p21WAF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Minimization of a polypeptide hormone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
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7 January 2021
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Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 mutations in human immortalized epithelial cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
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Signalling targets for anticancer drug development
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
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7 January 2021
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Pharmaceutical research in molecular oncology
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stated in
Crossref
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7 January 2021
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Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic
1 reference
stated in
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retrieved
7 January 2021
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inferred from DOI database lookup
The 3Rs of life: Ras, Raf and growth regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
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Phosphatidylinositol-3-OH kinase as a direct target of Ras
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
SH2 and SH3 domains
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis for the binding of proline-rich peptides to SH3 domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody-antigen complexes
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Human growth hormone and extracellular domain of its receptor: crystal structure of the complex
1 reference
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7 January 2021
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Thermodynamic analysis of an antibody functional epitope
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1 reference
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Cloning and characterization of the Xenopus cyclin-dependent kinase inhibitor p27XIC1.
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
p21-containing cyclin kinases exist in both active and inactive states
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900029-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0960-9822(06)00029-7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
PubMed publication ID
8999999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8999999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8999999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
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