(Q42813579)

7 November 2017

title

Human recombinant heat shock protein 70 affects the maturation pathways of dendritic cells in vitro and has an in vivo adjuvant activity (English)

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7 November 2017

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Patrizia Rovere-Querini

5

object named as

Patrizia Rovere-Querini

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7 November 2017

Barbara Valentinis

1

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7 November 2017

Annalisa Capobianco

2

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7 November 2017

Francesca Esposito

3

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7 November 2017

Alessandro Bianchi

4

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7 November 2017

Angelo A Manfredi

6

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7 November 2017

Catia Traversari

7

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7 November 2017

publication date

2 May 2008

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Journal of Leukocyte Biology

7 November 2017

published in

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7 November 2017

volume

84

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7 November 2017

issue

1

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7 November 2017

page(s)

199-206

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Roles of heat-shock proteins in innate and adaptive immunity

7 November 2017

cites work

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Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses

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Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis

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Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways

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Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells.

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Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression

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Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells.

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Re-evaluating the role of heat-shock protein-peptide interactions in tumour immunity

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Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

21 January 2018

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Stimulation of Th1-polarizing cytokines, C-C chemokines, maturation of dendritic cells, and adjuvant function by the peptide binding fragment of heat shock protein 70.

21 January 2018

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The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo

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Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70

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CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin

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CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokines

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CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes

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Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells.

21 January 2018

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A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers

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Identification of stimulating and inhibitory epitopes within the heat shock protein 70 molecule that modulate cytokine production and maturation of dendritic cells.

21 January 2018

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Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70

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Direct effects of polymyxin B on human dendritic cells maturation. The role of IkappaB-alpha/NF-kappaB and ERK1/2 pathways and adhesion

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Essential roles of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4

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Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells

21 January 2018

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Immunobiology of dendritic cells

21 January 2018

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Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators

21 January 2018

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Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures

21 January 2018

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Maturation-dependent expression and function of the CD49d integrin on monocyte-derived human dendritic cells

21 January 2018

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Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages

21 January 2018

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The IkappaB kinase complex and NF-kappaB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1.

21 January 2018

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Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4.

21 January 2018

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Factors and signals that govern the migration of dendritic cells via lymphatics: recent advances

21 January 2018

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The heat shock proteins, Hsp70 and Hsp83, of Leishmania infantum are mitogens for mouse B cells

21 January 2018

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Toxoplasma gondii-derived heat shock protein HSP70 functions as a B cell mitogen

21 January 2018

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21 January 2018

Identifiers

DOI

10.1189/JLB.0807548

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7 November 2017

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