(Q42813806)

7 November 2017

Chemical modifications in therapeutic protein aggregates generated under different stress conditions (English)

1 reference

7 November 2017

Quanzhou Luo

1

1 reference

7 November 2017

Marisa K Joubert

2

1 reference

7 November 2017

Riki Stevenson

3

1 reference

7 November 2017

Randal R Ketchem

4

1 reference

7 November 2017

Linda O Narhi

5

1 reference

7 November 2017

Jette Wypych

6

1 reference

7 November 2017

language of work or name

English

0 references

publication date

25 April 2011

1 reference

Journal of Biological Chemistry

7 November 2017

1 reference

7 November 2017

286

1 reference

7 November 2017

28

1 reference

7 November 2017

25134-25144

1 reference

Classification and characterization of therapeutic antibody aggregates

7 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Precipitation of a monoclonal antibody by soluble tungsten

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Antibodies for the treatment of bacterial infections: current experience and future prospects

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Protein aggregation: pathways, induction factors and analysis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Mass spectrometry for structural characterization of therapeutic antibodies

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Spontaneous asparaginyl deamidation of canine milk lysozyme under mild conditions

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Heterogeneity of monoclonal antibodies

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Downstream processing of monoclonal antibodies--application of platform approaches

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Antibody targeted drugs as cancer therapeutics

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Where disease pathogenesis meets protein formulation: renal deposition of immunoglobulin aggregates.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

De novo peptide sequencing based on a divide-and-conquer algorithm and peptide tandem spectrum simulation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Announcing the worldwide Protein Data Bank

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Stereochemistry of polypeptide chain configurations

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony‐stimulating factor

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Current and prospective applications of metal ion-protein binding

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Therapeutic antibodies for human diseases at the dawn of the twenty-first century

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Deamidation of human proteins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Antibodies have the intrinsic capacity to destroy antigens

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

The effects of alpha-helix on the stability of Asn residues: deamidation rates in peptides of varying helicity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Identification of tryptophan oxidation products in bovine alpha-crystallin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Tungsten-induced protein aggregation: solution behavior

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Human antibody Fc deamidation in vivo.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Methionine, tryptophan, and histidine oxidation in a model protein, PTH: mechanisms and stabilization

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

The oxidation of yeast alcohol dehydrogenase-1 by hydrogen peroxide in vitro

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

In vivo deamidation characterization of monoclonal antibody by LC/MS/MS.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Development of a methodology based on metal-catalyzed oxidation reactions and mass spectrometry to determine the metal binding sites in copper metalloproteins

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Immunogenic Cu2+-induced biopolymer systems comprising a steroid hormone, protein antigen, and synthetic polyelectrolytes

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Antibody catalysis of the oxidation of water

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137086

Antibody Response to Aggregated Human Interferon Alpha2b in Wild-type and Transgenic Immune Tolerant Mice Depends on Type and Level of Aggregation

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M110.160440

Mechanisms of metal-catalyzed oxidation of histidine to 2-oxo-histidine in peptides and proteins

21 January 2018

1 reference

12 December 2020

Aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation

1 reference

12 December 2020

Changes in the histidine residues of Cu/Zn superoxide dismutase during aging

1 reference

12 December 2020

Adverse effects of intravenous immunoglobulin therapy

1 reference

12 December 2020

Metal-catalyzed oxidation of histidine in human growth hormone. Mechanism, isotope effects, and inhibition by a mild denaturing alcohol

1 reference

12 December 2020

Protein aggregates seem to play a key role among the parameters influencing the antigenicity of interferon alpha (IFN-alpha) in normal and transgenic mice

1 reference

12 December 2020

Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2

1 reference

12 December 2020

Affinity cleavage at the metal-binding site of phosphoenolpyruvate carboxykinase

1 reference

12 December 2020

Induction and analysis of aggregates in a liquid IgG1-antibody formulation

1 reference

12 December 2020

Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature

1 reference

12 December 2020

Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody

1 reference

12 December 2020

Shaken, not stirred: mechanical stress testing of an IgG1 antibody

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.160440

1 reference

7 November 2017

1 reference

7 November 2017

PubMed publication ID

21518762

1 reference